Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   E5A72_RS09275 Genome accession   NZ_CP039025
Coordinates   1885938..1887164 (-) Length   408 a.a.
NCBI ID   WP_000279216.1    Uniprot ID   A0A009IRK3
Organism   Acinetobacter baumannii ATCC 17978 substr. PMR-High     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1880938..1892164
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5A72_RS09245 (E5A72_09245) - 1880966..1882276 (+) 1311 WP_000753297.1 tetratricopeptide repeat protein -
  E5A72_RS09250 (E5A72_09250) - 1882353..1882679 (+) 327 WP_000099685.1 pyrimidine/purine nucleoside phosphorylase -
  E5A72_RS09255 (E5A72_09255) rlmB 1882781..1883530 (+) 750 WP_001118149.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  E5A72_RS09260 (E5A72_09260) - 1883566..1884483 (+) 918 WP_000075016.1 DMT family transporter -
  E5A72_RS09265 (E5A72_09265) coaE 1884480..1885076 (-) 597 WP_000874127.1 dephospho-CoA kinase -
  E5A72_RS19920 (E5A72_09270) pilD 1885078..1885938 (-) 861 WP_001152268.1 prepilin peptidase Machinery gene
  E5A72_RS09275 (E5A72_09275) pilC 1885938..1887164 (-) 1227 WP_000279216.1 type II secretion system F family protein Machinery gene
  E5A72_RS09280 (E5A72_09280) pilB 1887194..1888906 (-) 1713 WP_001274983.1 type IV-A pilus assembly ATPase PilB Machinery gene
  E5A72_RS09285 (E5A72_09285) tpiA 1889197..1889991 (+) 795 WP_000016939.1 triose-phosphate isomerase -
  E5A72_RS09290 (E5A72_09290) secG 1890004..1890333 (+) 330 WP_000555570.1 preprotein translocase subunit SecG -
  E5A72_RS09305 (E5A72_09305) rimP 1890809..1891333 (+) 525 WP_000777730.1 ribosome maturation factor RimP -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44936.43 Da        Isoelectric Point: 9.9566

>NTDB_id=356796 E5A72_RS09275 WP_000279216.1 1885938..1887164(-) (pilC) [Acinetobacter baumannii ATCC 17978 substr. PMR-High]
MAVKKAQMMPTFAYEGVDRKGVKIKGELPAKNMALAKVTLRKQGVTVRNIREKRKNILEGLFKKKVTTLDITIFTRQLAT
MMKAGVPLVQGFEIVAEGLENPAMREVVLGIKGEVEGGSTFASALRKYPQHFDNLFCSLVESGEQSGALETMLDRVAIYK
EKSELLKQKIKKAMKYPATVIVVAIVVTIILMVKVVPVFQDLFASFGADLPAFTQMVVNMSKWMQEYWFIMIIAIGAVIA
AFLEAKKRSKKFRDGLDKLALKLPIFGDLVYKAIIARYSRTLATTFAAGVPLIDALESTAGATNNVIYEKAVMKIREDVA
TGQQLQFAMRVSNRFPSMAIQMVAIGEESGALDSMLDKVATYYENEVDNAVDGLTSMMEPLIMAILGVLVGGLVIAMYLP
IFQMGSVV

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=356796 E5A72_RS09275 WP_000279216.1 1885938..1887164(-) (pilC) [Acinetobacter baumannii ATCC 17978 substr. PMR-High]
ATGGCTGTCAAAAAGGCACAAATGATGCCGACTTTTGCTTATGAAGGGGTTGACCGTAAGGGCGTAAAAATCAAGGGAGA
ACTTCCGGCTAAAAACATGGCCTTAGCCAAAGTAACCTTACGCAAACAAGGGGTGACTGTTCGAAATATACGTGAAAAAC
GTAAAAATATTCTTGAAGGTTTATTCAAGAAAAAAGTCACCACACTCGATATTACGATTTTTACTCGACAATTGGCGACC
ATGATGAAAGCTGGTGTACCACTCGTACAAGGCTTTGAAATTGTAGCTGAAGGTTTAGAAAACCCGGCCATGCGTGAGGT
TGTACTCGGTATTAAAGGTGAAGTCGAAGGTGGTAGTACTTTTGCCTCAGCTTTAAGAAAATATCCTCAACATTTTGATA
ACTTGTTTTGTTCACTTGTTGAGTCTGGTGAACAATCAGGCGCACTCGAAACGATGCTGGACCGCGTTGCAATTTACAAA
GAAAAAAGTGAGTTGCTCAAGCAAAAAATCAAGAAAGCAATGAAATACCCAGCAACAGTTATTGTAGTAGCCATTGTGGT
GACCATTATTTTGATGGTTAAAGTAGTTCCCGTTTTCCAAGATTTATTTGCGTCTTTTGGAGCAGATTTACCTGCATTTA
CGCAAATGGTTGTGAATATGTCGAAATGGATGCAGGAATACTGGTTTATTATGATTATTGCGATTGGCGCAGTCATTGCT
GCCTTTCTGGAAGCAAAAAAACGCAGTAAAAAGTTTCGTGATGGCTTAGATAAACTGGCGCTTAAGTTACCTATTTTTGG
GGACTTGGTTTATAAAGCAATTATTGCCCGCTATAGCCGCACGCTTGCTACAACATTTGCCGCAGGTGTTCCACTTATTG
ATGCATTAGAATCGACTGCTGGCGCAACCAATAACGTGATTTATGAAAAAGCTGTGATGAAAATTCGTGAAGATGTCGCA
ACGGGTCAACAGCTTCAGTTTGCTATGCGGGTCTCTAATCGTTTTCCATCTATGGCTATACAAATGGTTGCAATTGGTGA
AGAATCGGGTGCACTAGACAGCATGCTCGATAAAGTTGCCACTTATTATGAAAATGAAGTGGATAATGCCGTTGATGGTT
TAACCTCTATGATGGAACCTTTAATTATGGCAATTTTAGGGGTGCTCGTAGGCGGTCTGGTAATTGCTATGTATCTTCCA
ATTTTCCAAATGGGCTCAGTTGTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(279-400)

Type II secretion system (T2SS), protein F (T2SSF)

(74-197)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A009IRK3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Acinetobacter baumannii D1279779

99.755

100

0.998
  pilC Acinetobacter baylyi ADP1

86.029

100

0.86
  pilC Pseudomonas stutzeri DSM 10701

59.753

99.265

0.593
  pilC Legionella pneumophila strain ERS1305867

53.827

99.265

0.534
  pilG Neisseria gonorrhoeae MS11

47.236

97.549

0.461
  pilG Neisseria meningitidis 44/76-A

47.236

97.549

0.461
  pilC Vibrio cholerae strain A1552

42.647

100

0.426
  pilC Vibrio campbellii strain DS40M4

41.089

99.02

0.407
  pilC Thermus thermophilus HB27

36.658

98.284

0.36

Multiple sequence alignment