Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA/cilB/dalA   Type   Machinery gene
Locus tag   ES276_RS07930 Genome accession   NZ_CP038252
Coordinates   1563605..1564441 (-) Length   278 a.a.
NCBI ID   WP_238092981.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901936     
Function   ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology)   
DNA processing Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IS/Tn 1562089..1563033 1563605..1564441 flank 572


Gene organization within MGE regions


Location: 1562089..1564441
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ES276_RS07925 (ES276_08440) - 1562089..1563033 (+) 945 WP_238092978.1 IS30-like element ISSpn8 family transposase -
  ES276_RS07930 (ES276_08450) dprA/cilB/dalA 1563605..1564441 (-) 837 WP_238092981.1 DNA-processing protein DprA Machinery gene

Sequence

Protein


Download         Length: 278 a.a.        Molecular weight: 30680.29 Da        Isoelectric Point: 5.2064

>NTDB_id=352643 ES276_RS07930 WP_238092981.1 1563605..1564441(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901936]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAALQNGGKTIAV
IGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEEGRDV
FAIPASILDGLSDGCHHLIQEGAKLLTSGQDVLAEFEF

Nucleotide


Download         Length: 837 bp        

>NTDB_id=352643 ES276_RS07930 WP_238092981.1 1563605..1564441(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901936]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCTTCAGAATGGCGGAAAAACCATTGCAGTG
ATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGACCATCTGGTTCT
AAGTGAATATGGACCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTGGACTTTGTCGTG
GTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAAGGACGCGATGTC
TTTGCTATTCCTGCTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGCAAAATTGCTCAC
CAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(75-267)

DNA processing protein A sterile alpha motif domain (SAM_DprA)

(3-64)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA/cilB/dalA Streptococcus pneumoniae Rx1

97.872

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae D39

97.872

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae R6

97.872

100

0.993
  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

97.872

100

0.993
  dprA/cilB/dalA Streptococcus mitis NCTC 12261

96.454

100

0.978
  dprA/cilB/dalA Streptococcus mitis SK321

95.745

100

0.971
  dprA Streptococcus mutans UA159

62.143

100

0.626
  dprA Lactococcus lactis subsp. cremoris KW2

54.643

100

0.55
  dprA Staphylococcus aureus N315

36.749

100

0.374

Multiple sequence alignment