Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   E3306_RS07635 Genome accession   NZ_CP038183
Coordinates   1589061..1590035 (-) Length   324 a.a.
NCBI ID   WP_000697217.1    Uniprot ID   A0AAN2D5C1
Organism   Staphylococcus aureus strain MJ015     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1584061..1595035
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E3306_RS07595 (E3306_07935) gcvT 1584562..1585653 (-) 1092 WP_000093349.1 glycine cleavage system aminomethyltransferase GcvT -
  E3306_RS07600 (E3306_07940) - 1585812..1586336 (-) 525 WP_001015120.1 shikimate kinase -
  E3306_RS07605 (E3306_07945) - 1586326..1586472 (-) 147 WP_001792109.1 hypothetical protein -
  E3306_RS07610 (E3306_07950) comGF 1586569..1587066 (-) 498 WP_001788897.1 competence type IV pilus minor pilin ComGF Machinery gene
  E3306_RS07615 (E3306_07955) comGE 1586984..1587283 (-) 300 WP_000844410.1 hypothetical protein Machinery gene
  E3306_RS07620 (E3306_07960) comGD 1587270..1587716 (-) 447 WP_001788899.1 competence type IV pilus minor pilin ComGD Machinery gene
  E3306_RS07625 (E3306_07965) comGC 1587694..1588005 (-) 312 WP_000472256.1 competence type IV pilus major pilin ComGC Machinery gene
  E3306_RS07630 (E3306_07970) comGB 1588019..1589089 (-) 1071 WP_000776422.1 competence type IV pilus assembly protein ComGB Machinery gene
  E3306_RS07635 (E3306_07975) comGA 1589061..1590035 (-) 975 WP_000697217.1 competence type IV pilus ATPase ComGA Machinery gene
  E3306_RS07640 (E3306_07980) - 1590087..1590710 (-) 624 WP_001223008.1 MBL fold metallo-hydrolase -
  E3306_RS07645 (E3306_07985) - 1590676..1591036 (-) 361 Protein_1510 MTH1187 family thiamine-binding protein -
  E3306_RS07650 (E3306_07990) - 1591036..1592024 (-) 989 Protein_1511 ROK family glucokinase -
  E3306_RS07655 (E3306_07995) - 1592021..1592222 (-) 202 Protein_1512 YqgQ family protein -
  E3306_RS07660 (E3306_08000) - 1592203..1593664 (-) 1462 Protein_1513 rhomboid family intramembrane serine protease -
  E3306_RS07665 (E3306_08005) - 1593676..1594215 (-) 540 WP_000164546.1 5-formyltetrahydrofolate cyclo-ligase -
  E3306_RS07670 (E3306_08010) rpmG 1594424..1594573 (-) 150 WP_001265709.1 50S ribosomal protein L33 -

Sequence

Protein


Download         Length: 324 a.a.        Molecular weight: 36869.90 Da        Isoelectric Point: 8.8516

>NTDB_id=352174 E3306_RS07635 WP_000697217.1 1589061..1590035(-) (comGA) [Staphylococcus aureus strain MJ015]
MKILFQEIINKAIEMKASDVHFIPVKNEVSIKFRINDNLEQYEQIGNSIYQKLLVYMKFQAGLDVSTQQVAQSGRYSYHF
NKIYFLRISTLPLSLGQESCVIRIAPQFFQQQKSTYKFNDFKHLMNKKQGLLLFSGPTGSGKSTLMYQMVSYANKALNLN
VISIEDPVEMQIPGIVQINVNDKAGINYVNSFKAILRCDPDVILIGEIRDKDVAKCVIQASLSGHLVLTTLHATDCKGAI
LRLLEMGISVQELIQATNLIINQRLVTTIKQQRQLVCEILSQQQLRYFFSHNHSLPSSFKNLEDKLDDMTKAGVICETTM
DKYI

Nucleotide


Download         Length: 975 bp        

>NTDB_id=352174 E3306_RS07635 WP_000697217.1 1589061..1590035(-) (comGA) [Staphylococcus aureus strain MJ015]
TTGAAGATTCTATTTCAAGAAATAATTAATAAAGCGATAGAAATGAAAGCGAGTGATGTACATTTTATTCCAGTTAAAAA
TGAAGTAAGTATTAAATTTAGAATTAATGATAACTTGGAGCAGTATGAACAAATTGGGAATAGCATTTATCAAAAGTTAT
TAGTTTATATGAAGTTTCAAGCTGGGCTTGATGTTTCTACACAGCAAGTCGCACAGAGCGGTCGATATAGTTACCATTTC
AATAAAATATATTTTTTGAGAATATCAACTTTACCATTGTCACTTGGCCAAGAAAGTTGTGTTATCAGAATTGCACCTCA
ATTTTTTCAACAACAGAAATCAACTTATAAATTCAATGATTTTAAACACCTCATGAATAAGAAACAAGGATTACTATTGT
TTAGTGGGCCAACTGGTTCAGGAAAGAGTACATTAATGTATCAAATGGTCTCATACGCGAATAAAGCCTTGAATTTAAAT
GTAATTTCTATAGAGGATCCTGTAGAGATGCAAATTCCTGGTATCGTCCAAATTAATGTGAATGATAAAGCTGGCATTAA
CTATGTAAATTCGTTTAAAGCTATTTTAAGATGTGATCCTGATGTTATTTTAATAGGTGAAATCAGAGATAAAGATGTTG
CCAAGTGTGTTATACAGGCTAGTTTAAGTGGTCACCTGGTTCTGACTACATTGCATGCAACTGATTGTAAAGGTGCTATT
TTAAGGCTATTAGAAATGGGCATTTCTGTACAAGAATTGATACAGGCAACTAATTTAATTATAAACCAACGACTTGTAAC
TACTATTAAGCAACAGCGACAATTAGTATGTGAAATTCTATCTCAGCAACAACTCCGATATTTCTTTTCCCATAATCATT
CATTACCATCATCATTTAAGAACTTAGAAGATAAACTTGATGATATGACAAAAGCAGGTGTCATTTGTGAAACTACAATG
GATAAATACATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(7-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Staphylococcus aureus MW2

99.691

100

0.997
  comGA Staphylococcus aureus N315

99.691

100

0.997

Multiple sequence alignment