Detailed information NTG0351384

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: E3C75_RS01920
• Genome accession: NZ_CP038020
• Coordinates: 360613..361848 (+)
• Length: 411 a.a.
• NCBI ID: WP_111679766.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ATCC 19258
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 355613..366848

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3C75_RS01890	-	356079..358685 (+)	2607	WP_111679764.1	YfhO family protein	-
E3C75_RS01910	-	359230..359913 (-)	684	WP_111679765.1	YoaK family protein	-
E3C75_RS01915	rlmH	359929..360408 (-)	480	WP_084829195.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
E3C75_RS01920	htrA	360613..361848 (+)	1236	WP_111679766.1	trypsin-like peptidase domain-containing protein	Regulator
E3C75_RS01925	spo0J	361914..362681 (+)	768	WP_133264061.1	ParB/RepB/Spo0J family partition protein	Regulator
E3C75_RS01930	dnaA	362920..364284 (+)	1365	WP_084828394.1	chromosomal replication initiator protein DnaA	-
E3C75_RS01935	dnaN	364430..365566 (+)	1137	WP_011226715.1	DNA polymerase III subunit beta	-
E3C75_RS01940	-	365617..365808 (+)	192	WP_084828396.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 411 a.a.
• Molecular weight: 42817.06 Da
• Isoelectric Point: 4.7061

>NTDB_id=351384 E3C75_RS01920 WP_111679766.1 360613..361848(+) (htrA) [Streptococcus thermophilus strain ATCC 19258]
MKKFNWKKIVAPIAMLVIGLLGGLLGAFILLTAAGVSFTNTTDTGVKTAKTVYTNITDTTKAVKKAQNAVVSVINYQEGS
SSDSLNDLYGRIFGGGDSSDSSQENSKDSDGLQVAGEGSGVIYKKDGKEAYIVTNNHVVDGAKKLEIMLSDGSKITGELV
GKDTYSDLAVVKVSSDKITTVAEFADSNSLTVGEKAIAIGSPLGTEYANSVTEGIVSSLSRTITMQNDNGETVSTNAIQT
DAAINPGNSGGALVNIEGQVIGINSSKISSTSAVAGSAVEGMGFAIPSNDVVEIINQLEKDGKVTRPALGISIADLNSLS
SSATSKLDLPDEVKSGVVVGSVQKGMPADGKLQEYDVITEIDGKKISSKTDIQTNLYSHSIGDTIKVTFYRGKDKKTVDL
KLTKSTEDISD

Nucleotide

• Length: 1236 bp

>NTDB_id=351384 E3C75_RS01920 WP_111679766.1 360613..361848(+) (htrA) [Streptococcus thermophilus strain ATCC 19258]
ATGAAAAAATTTAACTGGAAAAAAATAGTCGCGCCAATTGCAATGCTAGTTATTGGCTTACTAGGGGGTTTACTTGGTGC
CTTTATCCTACTAACAGCAGCCGGGGTATCTTTTACCAATACAACAGATACTGGAGTAAAAACGGCTAAGACCGTCTACA
CCAATATAACAGATACAACTAAGGCTGTTAAGAAAGCACAAAATGCCGTTGTTTCTGTCATCAATTATCAAGAAGGTTCA
TCTTCAGATTCTCTAAATGACCTTTATGGCCGTATCTTTGGCGGAGGGGACAGTTCTGATTCTAGCCAAGAAAATTCAAA
AGATTCAGATGGTCTGCAGGTCGCTGGTGAAGGTTCTGGAGTCATCTATAAAAAAGATGGCAAAGAAGCCTACATCGTAA
CCAATAACCACGTTGTCGATGGGGCTAAAAAACTTGAAATCATGCTTTCGGATGGTTCGAAAATTACTGGTGAACTTGTT
GGTAAAGACACTTACTCTGACCTAGCAGTTGTCAAAGTATCTTCAGATAAAATAACAACTGTTGCAGAATTTGCAGACTC
AAACTCCCTTACTGTTGGTGAAAAAGCAATTGCTATCGGTAGCCCACTTGGTACCGAATACGCCAACTCAGTAACAGAAG
GAATCGTTTCTAGTCTTAGCCGTACTATAACGATGCAAAACGATAATGGTGAAACTGTATCAACAAACGCTATCCAAACA
GATGCAGCCATTAACCCTGGTAACTCTGGTGGTGCCCTAGTCAATATTGAAGGACAAGTTATCGGTATTAACTCAAGTAA
AATTTCATCAACGTCTGCAGTCGCTGGTAGTGCTGTTGAAGGTATGGGGTTTGCCATTCCATCAAACGATGTTGTTGAAA
TCATCAATCAATTAGAAAAAGATGGTAAAGTTACACGACCAGCACTAGGGATCTCAATAGCAGATCTTAATAGCCTTTCT
AGCAGCGCAACTTCTAAATTAGATTTACCAGATGAGGTCAAATCCGGTGTTGTTGTCGGTAGTGTTCAGAAAGGTATGCC
AGCTGACGGTAAACTTCAAGAATATGATGTTATCACTGAGATTGATGGTAAGAAGATTAGCTCAAAAACTGATATTCAAA
CCAATCTTTACAGCCATAGTATCGGAGATACTATCAAGGTAACCTTCTATCGTGGTAAAGATAAGAAAACTGTAGATCTT
AAATTAACAAAATCTACAGAAGACATATCTGATTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (118-263)

• Peptidase family M50 (Peptidase_M50) (4-406)

• PDZ domain (PDZ_2) (307-402)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	61.787	98.054	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.039	100	0.572
htrA	Streptococcus mitis NCTC 12261	53.79	99.513	0.535
htrA	Streptococcus pneumoniae TIGR4	53.545	99.513	0.533
htrA	Streptococcus pneumoniae D39	53.545	99.513	0.533
htrA	Streptococcus pneumoniae Rx1	53.545	99.513	0.533
htrA	Streptococcus pneumoniae R6	53.545	99.513	0.533