Detailed information NTG0034988

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: NMO_RS10610
• Genome accession: NC_013016
• Coordinates: 2061326..2062513 (-)
• Length: 395 a.a.
• NCBI ID: WP_015815969.1
• Uniprot ID: C6S9I0
• Organism: Neisseria meningitidis alpha14
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 2056326..2067513

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMO_RS10585 (NMO_1916)	-	2056625..2057002 (-)	378	WP_002233408.1	helix-turn-helix domain-containing protein	-
NMO_RS10595 (NMO_1918)	-	2057693..2058388 (+)	696	WP_002233407.1	hypothetical protein	-
NMO_RS10600 (NMO_1919)	topA	2058461..2060767 (-)	2307	WP_002234458.1	type I DNA topoisomerase	-
NMO_RS10605 (NMO_1920)	-	2060839..2061300 (-)	462	WP_002215351.1	DUF494 domain-containing protein	-
NMO_RS10610 (NMO_1921)	dprA	2061326..2062513 (-)	1188	WP_015815969.1	DNA-processing protein DprA	Machinery gene
NMO_RS10615 (NMO_1922)	-	2062604..2063881 (-)	1278	WP_015815970.1	sigma-54-dependent transcriptional regulator	-
NMO_RS10620 (NMO_1923)	-	2063874..2065991 (-)	2118	WP_015815971.1	sensor histidine kinase	-
NMO_RS10625 (NMO_1924)	-	2065991..2066590 (-)	600	WP_002216221.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 395 a.a.
• Molecular weight: 41815.84 Da
• Isoelectric Point: 6.1732

>NTDB_id=34988 NMO_RS10610 WP_015815969.1 2061326..2062513(-) (dprA) [Neisseria meningitidis alpha14]
MTEDERFAWLQLAFTPYIGAESFLLLLRRFGSASNALSAPAEQVAPAVRHKQAAEAWRNAEKRALARQAAEAALEWEMRD
GCRLMLLQDEDFPEMLTQGLTAPPVLFLRGNVRLLHKPSAAIVGSRHATPQAMRIAKDFGRALGEKGIPVVSGMASGIDT
AAHQGALQAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITAGLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLTECLDDILNECPGLLQNTGASSYSINKDTSDTGSRAVQA
AYAPPPAAKMPSEGAAGGTAVGGILDKMGFDPIHPDVLAGQLAMPAADLYAALLELELDGSVAAMPGGRYQRIRT

Nucleotide

• Length: 1188 bp

>NTDB_id=34988 NMO_RS10610 WP_015815969.1 2061326..2062513(-) (dprA) [Neisseria meningitidis alpha14]
ATGACAGAGGACGAACGTTTCGCGTGGCTGCAATTGGCGTTTACGCCCTATATCGGCGCGGAAAGCTTCCTGCTGCTGCT
GCGCCGTTTCGGCAGCGCGTCAAACGCCCTGTCCGCACCGGCGGAACAGGTCGCCCCGGCGGTGCGGCACAAGCAGGCGG
CCGAGGCTTGGCGCAATGCGGAAAAACGCGCTTTGGCGCGGCAGGCGGCAGAAGCGGCGTTGGAATGGGAAATGCGGGAC
GGATGCCGCCTGATGCTGCTTCAGGATGAAGATTTCCCCGAAATGCTGACGCAGGGGCTGACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCGGCTGCTGCACAAGCCTTCCGCCGCCATCGTCGGCAGCCGCCATGCCACGCCGCAGGCGATGC
GGATTGCCAAAGATTTCGGCAGGGCGTTGGGAGAGAAAGGCATTCCCGTTGTGTCGGGTATGGCTTCGGGCATCGATACC
GCCGCCCATCAGGGTGCGTTGCAGGCGGAAGGCGGCACCATCGCCGTGTGGGGGACGGGCATAGACCGCATTTATCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGACTGATTGTCAGCGAGTTCCCCATCGGCACGCGCCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCGCTGTCGCAGGTTACGCTGGTGGTTGAAGCCGCGTTGGAATCC
GGTTCGCTGATTACCGCCGGCCTGGCGGCAGAAATGGGGCGCGAAGTGATGGCGGTACCCGGTTCGATAGACAATCCACA
CAGCAAAGGCTGCCACAAACTGATTAAAGACGGCGCGAAACTGACGGAATGTTTGGACGACATCCTGAACGAATGCCCGG
GTCTATTGCAAAATACGGGTGCTTCGTCATATTCTATAAATAAGGATACGTCCGACACGGGCAGCCGCGCCGTTCAGGCG
GCATACGCCCCGCCGCCTGCCGCAAAAATGCCGTCTGAAGGGGCGGCAGGCGGCACAGCCGTCGGCGGCATACTGGATAA
AATGGGTTTCGACCCCATCCATCCCGACGTGCTTGCCGGACAGTTGGCTATGCCTGCCGCAGATTTGTATGCCGCACTGT
TGGAATTGGAATTGGACGGCAGCGTTGCCGCAATGCCCGGCGGCAGATACCAGCGTATCCGAACTTGA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (79-282)

• DprA winged helix domain (DprA_WH) (341-388)

3D structure

• AlphaFold DB: C6S9I0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria gonorrhoeae MS11	96.709	100	0.967
dprA	Neisseria gonorrhoeae strain FA1090	96.456	100	0.965
dprA	Neisseria meningitidis strain C311	89.673	100	0.901
dprA	Neisseria meningitidis MC58	89.673	100	0.901
dprA	Glaesserella parasuis strain SC1401	40.576	96.709	0.392
dprA	Vibrio cholerae strain A1552	37.975	100	0.38