Detailed information NTG0349466

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: EZ612_RS04535
• Genome accession: NZ_CP036531
• Coordinates: 887520..888356 (+)
• Length: 278 a.a.
• NCBI ID: WP_031488274.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain STAB10048
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 882520..893356

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EZ612_RS04505 (EZ612_04570)	-	883005..883442 (+)	438	WP_031488279.1	hypothetical protein	-
EZ612_RS04510 (EZ612_04575)	-	883492..884403 (-)	912	WP_031488278.1	diacylglycerol/lipid kinase family protein	-
EZ612_RS04515 (EZ612_04580)	trhA	884520..885170 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
EZ612_RS04520 (EZ612_04585)	-	885167..885607 (-)	441	WP_031488277.1	DUF1836 domain-containing protein	-
EZ612_RS04525 (EZ612_04590)	ylqF	885826..886674 (+)	849	WP_031488276.1	ribosome biogenesis GTPase YlqF	-
EZ612_RS04530 (EZ612_04595)	-	886664..887455 (+)	792	WP_031488275.1	ribonuclease HII	-
EZ612_RS04535 (EZ612_04600)	dprA	887520..888356 (+)	837	WP_031488274.1	DNA-processing protein DprA	Machinery gene
EZ612_RS04540 (EZ612_04605)	topA	888463..890592 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
EZ612_RS08560	-	890667..891524 (-)	858	Protein_852	LysR family transcriptional regulator	-
EZ612_RS04555 (EZ612_04620)	-	891564..892109 (+)	546	Protein_853	PTS sugar transporter subunit IIC	-
EZ612_RS04560 (EZ612_04625)	-	892124..893116 (+)	993	WP_031488271.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30960.96 Da
• Isoelectric Point: 9.2511

>NTDB_id=349466 EZ612_RS04535 WP_031488274.1 887520..888356(+) (dprA) [Streptococcus pyogenes strain STAB10048]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVITEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=349466 EZ612_RS04535 WP_031488274.1 887520..888356(+) (dprA) [Streptococcus pyogenes strain STAB10048]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGCTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGATAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363