Detailed information NTG0034578

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: SSUSC84_RS07905
• Genome accession: NC_012924
• Coordinates: 1595354..1596403 (-)
• Length: 349 a.a.
• NCBI ID: WP_012775295.1
• Uniprot ID: A0A2K1T047
• Organism: Streptococcus suis SC84
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1590354..1601403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSUSC84_RS07885 (SSUSC84_1512)	nadE	1590760..1591584 (+)	825	WP_004194617.1	ammonia-dependent NAD(+) synthetase	-
SSUSC84_RS07890 (SSUSC84_1513)	-	1592880..1593407 (-)	528	WP_012027591.1	VanZ family protein	-
SSUSC84_RS07895 (SSUSC84_1514)	rlmN	1593404..1594516 (-)	1113	WP_012028433.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
SSUSC84_RS07900 (SSUSC84_1515)	-	1594525..1595166 (-)	642	WP_012027595.1	YutD family protein	-
SSUSC84_RS07905 (SSUSC84_1516)	sepM	1595354..1596403 (-)	1050	WP_012775295.1	SepM family pheromone-processing serine protease	Regulator
SSUSC84_RS07910 (SSUSC84_1517)	coaD	1596390..1596878 (-)	489	WP_012027597.1	pantetheine-phosphate adenylyltransferase	-
SSUSC84_RS07915 (SSUSC84_1518)	rsmD	1596868..1597407 (-)	540	WP_009910569.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
SSUSC84_RS07920 (SSUSC84_1519)	-	1597715..1598437 (-)	723	WP_012027598.1	lipoprotein	-
SSUSC84_RS07925 (SSUSC84_1520)	-	1598494..1598880 (-)	387	WP_004194735.1	rhodanese-like domain-containing protein	-
SSUSC84_RS07930 (SSUSC84_1521)	-	1598880..1599098 (-)	219	WP_004194736.1	YqgQ family protein	-
SSUSC84_RS07935 (SSUSC84_1522)	-	1599406..1600008 (-)	603	WP_012027601.1	response regulator transcription factor	-
SSUSC84_RS07940 (SSUSC84_1523)	-	1600005..1601099 (-)	1095	WP_012027602.1	sensor histidine kinase	-

Sequence

Protein

• Length: 349 a.a.
• Molecular weight: 37761.83 Da
• Isoelectric Point: 4.6112

>NTDB_id=34578 SSUSC84_RS07905 WP_012775295.1 1595354..1596403(-) (sepM) [Streptococcus suis SC84]
MKKNRKLTLIASIVLGTLLIWFAVFVRLPYYLESPGGAADIRQVLTVNNQIDQEDGSYNFTYVSVQQATALQLFAAQFDP
YTTVRSSEEMTGGADNEEYFRIARFYMETSQNMAKYQGLTLAGKEVNLDFFGVYVLALTDDSTFKKVLNIADTVVSINGK
TFESSPDLIKYVSGLEVGSDVTVGYISAGQEKSADGKIIKLSNGKNGIGITLVDHTEVQSSIPIDFQTGDIGGPSAGLMF
TLAIYTQLAEPDLRDGRIIAGTGTIEQDGKVGDIGGADKKVISAAKSGASIFFVPNNPVDVEVLKKNPKAKTNYEEAKEA
AEKAGLDIEVVPVKTVQEAIDYLKKTKGE

Nucleotide

• Length: 1050 bp

>NTDB_id=34578 SSUSC84_RS07905 WP_012775295.1 1595354..1596403(-) (sepM) [Streptococcus suis SC84]
ATGAAGAAAAATAGGAAGTTAACCTTAATTGCATCTATTGTTTTAGGAACTCTTTTGATTTGGTTTGCCGTTTTTGTTCG
TCTGCCTTATTATCTGGAAAGTCCAGGTGGAGCTGCCGATATTCGTCAGGTACTAACGGTGAACAATCAAATAGACCAAG
AGGATGGCTCTTACAACTTCACCTATGTATCAGTCCAACAGGCTACAGCTTTACAACTATTCGCTGCTCAGTTTGATCCC
TATACGACAGTTCGTTCCTCTGAAGAGATGACAGGAGGGGCCGACAATGAGGAGTATTTCCGTATAGCACGGTTTTACAT
GGAGACATCGCAAAATATGGCGAAGTACCAAGGTTTGACCTTGGCAGGAAAAGAAGTCAATCTTGATTTCTTTGGTGTCT
ATGTGCTTGCCTTGACGGATGATTCAACCTTTAAAAAAGTTCTTAATATTGCCGACACTGTTGTGAGTATCAATGGAAAA
ACATTTGAGTCTTCTCCTGATTTGATTAAATATGTGAGTGGCTTGGAGGTTGGAAGTGATGTAACAGTTGGTTATATTAG
CGCTGGTCAGGAAAAATCTGCGGACGGTAAGATTATCAAATTGTCTAATGGCAAAAACGGGATAGGTATCACTCTCGTAG
ATCATACAGAGGTTCAAAGTTCGATTCCGATTGATTTCCAAACAGGAGATATTGGTGGTCCAAGTGCTGGTCTGATGTTT
ACACTTGCCATCTATACTCAACTCGCAGAGCCTGACTTACGTGATGGTCGGATTATTGCTGGTACGGGGACTATCGAGCA
GGATGGAAAAGTAGGTGACATTGGTGGGGCTGATAAGAAGGTCATTTCGGCAGCTAAGTCTGGTGCAAGTATCTTTTTTG
TACCAAACAATCCAGTTGATGTAGAAGTTTTGAAGAAAAATCCAAAGGCTAAAACGAACTATGAAGAAGCTAAGGAAGCA
GCCGAGAAAGCAGGTCTAGATATTGAGGTAGTTCCTGTGAAAACTGTTCAAGAGGCTATTGATTATTTGAAGAAAACAAA
GGGCGAGTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (132-195)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-315)

3D structure

• AlphaFold DB: A0A2K1T047

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	60.807	99.427	0.605