Detailed information NTG0345192

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: GFB63_RS02550
• Genome accession: NZ_CP045596
• Coordinates: 503996..506149 (-)
• Length: 717 a.a.
• NCBI ID: WP_157795756.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain TK-P3A
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 498996..511149

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GFB63_RS02515 (GFB63_02600)	-	499116..499346 (-)	231	WP_011226494.1	bacteriocin class II family protein	-
GFB63_RS02520 (GFB63_02605)	-	499702..499902 (-)	201	WP_011681569.1	hypothetical protein	-
GFB63_RS02525 (GFB63_02610)	-	499921..500097 (-)	177	WP_011681570.1	Blp family class II bacteriocin	-
GFB63_RS02530 (GFB63_02615)	-	500348..501085 (+)	738	WP_024010062.1	LytTR family DNA-binding domain-containing protein	-
GFB63_RS10445	comD/blpH	501616..502419 (+)	804	WP_228024405.1	ATP-binding protein	Regulator
GFB63_RS02540 (GFB63_02625)	-	502437..502598 (-)	162	WP_011681573.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
GFB63_RS02545 (GFB63_02630)	comB	502613..503980 (-)	1368	WP_011681574.1	bacteriocin secretion accessory protein	Regulator
GFB63_RS02550 (GFB63_02635)	comA/nlmT	503996..506149 (-)	2154	WP_157795756.1	peptide cleavage/export ABC transporter	Regulator
GFB63_RS02555 (GFB63_02650)	-	507163..508908 (-)	1746	WP_100262366.1	ABC transporter ATP-binding protein	-
GFB63_RS02560 (GFB63_02655)	-	508901..510658 (-)	1758	WP_024010065.1	ABC transporter ATP-binding protein	-
GFB63_RS10450 (GFB63_02660)	-	510846..511052 (-)	207	WP_011681579.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80624.45 Da
• Isoelectric Point: 6.8843

>NTDB_id=345192 GFB63_RS02550 WP_157795756.1 503996..506149(-) (comA/nlmT) [Streptococcus thermophilus strain TK-P3A]
MFRFRRTFVPQIDMRDCGVAALASVAKYYGSDYSLAHLRELAKTNKEGTTALGLVEAAKKIGFETRAIKAEMSLFEMEDV
PYPFIAHVNKDGKLQHYYVIYKSTKDYLIIGDPDPSVKVTKMTKERFEKEWTGITLFMGPEPSYKPHKDKKNGLWDFLPL
IFKQRSLIANIVFASLLVTLINILGSYYLQGILDEYVPNQMKSTLGIISIGLVVTYVLQQMMTFARDYLLTILSQRLTID
VILSYIRHIFELPMSFFATRRTGEVISRFSDANSIIDALASTILSLFLDFSIVIIVGGVLLIQNSNLFKLVLCSVPIYTL
IVFAFMKPFERMNHDVMQSNAMVNSAIIEDINGIETIKSLTSEEVCYQKIDGEFIDYLDNSFRLSKLSILQTSLKQGAQL
ILNVLILWTGAQLVMGNTISIGQLITFNMLLSYFTNPLENIINLQTKLQSAKVANTRLNEVYLIESEFGQSDDTYQEGIA
DGDITVTDLSYKYGFGRDTLTDVSLTIRQGEKISFVGVSGSGKTTLAKMLVNFYQPYKGHIDFNGQNISRIDKKTLRQHI
NYLPQQSYIFSGSVLENLTLGAARGITQADILKACEIAEIRQDIENMPMGFQTELSDGAGLSGGQKQRIALARALLTKSP
VLILDEATSGLDVLTEKQVIDNLLALKDKTIIFVAHRLSIAERTDRIVVIDHGRVVETGSHQDLMSYPGFYYQLFRK

Nucleotide

• Length: 2154 bp

>NTDB_id=345192 GFB63_RS02550 WP_157795756.1 503996..506149(-) (comA/nlmT) [Streptococcus thermophilus strain TK-P3A]
ATGTTTCGTTTTCGTAGGACTTTTGTCCCTCAAATAGACATGAGGGATTGTGGAGTTGCTGCCTTGGCATCAGTGGCCAA
GTACTATGGTTCAGATTATTCATTAGCACATCTGCGTGAGTTGGCGAAGACCAATAAAGAAGGGACAACTGCCTTAGGTC
TTGTAGAGGCTGCTAAAAAAATTGGCTTTGAAACGAGAGCTATAAAGGCTGAAATGTCGCTCTTTGAGATGGAAGATGTT
CCTTATCCTTTTATTGCTCATGTTAATAAAGATGGGAAGCTTCAACATTATTATGTTATTTATAAAAGCACCAAGGATTA
TCTGATAATTGGAGACCCTGATCCAAGTGTAAAAGTAACTAAAATGACTAAAGAGCGTTTTGAGAAAGAGTGGACAGGTA
TTACTCTTTTTATGGGACCGGAACCCAGTTATAAACCACATAAGGATAAGAAAAATGGACTCTGGGACTTTCTCCCTTTG
ATCTTTAAACAAAGGTCCTTGATAGCTAATATTGTCTTTGCCAGTCTCTTGGTTACTTTAATAAATATTTTAGGTTCCTA
TTATTTACAAGGTATTCTAGACGAATATGTCCCTAATCAAATGAAGTCTACCTTAGGAATTATCTCAATTGGATTAGTTG
TGACCTATGTTTTACAACAAATGATGACTTTTGCAAGAGATTATCTCTTAACCATACTGAGTCAGCGATTGACCATTGAC
GTTATCTTGTCCTACATACGACATATCTTTGAACTCCCAATGTCTTTTTTTGCCACAAGACGTACAGGGGAGGTTATCTC
ACGTTTTAGTGATGCTAACTCTATTATCGATGCTCTGGCTTCGACGATATTATCACTTTTCCTTGATTTCTCTATTGTGA
TTATCGTAGGAGGCGTGTTATTGATACAAAATAGCAATCTCTTCAAGCTAGTTCTTTGTTCGGTTCCAATTTATACCCTT
ATCGTCTTTGCCTTTATGAAACCTTTTGAGCGAATGAATCATGACGTCATGCAGAGTAATGCTATGGTTAATTCAGCCAT
CATTGAGGACATTAATGGGATTGAAACCATAAAGTCACTAACCAGCGAAGAAGTATGCTATCAAAAGATTGATGGTGAGT
TTATTGACTATCTAGACAATTCTTTTCGCCTTTCTAAGTTATCTATACTACAAACATCATTGAAACAAGGTGCTCAACTT
ATTTTAAATGTACTTATCCTCTGGACAGGTGCTCAGTTGGTGATGGGAAATACCATTTCGATAGGACAATTGATTACTTT
TAATATGTTGCTTTCTTACTTCACGAATCCTTTGGAAAATATCATTAACCTGCAAACCAAGTTACAGTCTGCTAAGGTAG
CTAATACTAGGCTCAATGAGGTCTATCTGATTGAATCAGAGTTTGGACAAAGTGATGATACCTATCAAGAAGGCATTGCG
GATGGAGATATCACTGTTACGGATTTATCTTATAAATATGGTTTTGGTCGTGATACTTTGACTGATGTCAGTTTGACGAT
TAGACAAGGAGAAAAAATCAGTTTTGTTGGTGTCAGTGGATCTGGTAAGACTACTCTAGCTAAAATGTTGGTCAATTTTT
ATCAACCATATAAGGGGCACATAGATTTTAATGGTCAAAATATTAGTCGCATAGACAAGAAAACTCTTCGTCAACATATT
AACTATCTCCCTCAGCAATCCTATATATTTAGTGGTAGTGTTTTAGAAAATCTTACTTTAGGTGCAGCACGGGGTATTAC
GCAAGCTGATATTTTGAAAGCTTGTGAAATAGCAGAAATTCGTCAAGATATTGAAAACATGCCTATGGGGTTTCAGACAG
AGCTGTCTGATGGAGCAGGTCTGTCTGGAGGGCAAAAGCAACGTATCGCTTTGGCGCGTGCACTACTAACGAAATCTCCT
GTACTAATCTTAGATGAAGCAACTAGCGGATTGGATGTTTTGACAGAAAAGCAGGTTATTGATAACCTCCTAGCACTAAA
AGATAAAACGATCATCTTTGTAGCACACAGGCTTAGTATCGCTGAGCGGACCGACCGTATCGTAGTCATTGATCACGGAC
GCGTAGTGGAGACAGGTTCTCATCAAGACCTAATGTCTTATCCAGGTTTCTATTATCAATTATTTAGAAAGTGA

Domains

Predicted by InterProScan.

• ABC transporter transmembrane region (ABC_membrane) (170-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.927	99.582	0.676
comA	Streptococcus mitis NCTC 12261	66.104	99.163	0.656
comA	Streptococcus pneumoniae Rx1	65.682	99.163	0.651
comA	Streptococcus pneumoniae D39	65.682	99.163	0.651
comA	Streptococcus pneumoniae R6	65.682	99.163	0.651
comA	Streptococcus mitis SK321	65.401	99.163	0.649
comA	Streptococcus pneumoniae TIGR4	65.26	99.163	0.647
comA	Streptococcus gordonii str. Challis substr. CH1	64.286	99.582	0.64