Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   GFB63_RS10445 Genome accession   NZ_CP045596
Coordinates   501616..502419 (+) Length   267 a.a.
NCBI ID   WP_228024405.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain TK-P3A     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 496616..507419
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GFB63_RS02500 (GFB63_02580) - 496889..497071 (+) 183 Protein_507 IS3 family transposase -
  GFB63_RS02505 (GFB63_02585) - 497217..497459 (-) 243 WP_011227518.1 Blp family class II bacteriocin -
  GFB63_RS11030 (GFB63_02590) - 497710..498111 (-) 402 WP_011226490.1 hypothetical protein -
  GFB63_RS02510 - 498966..499109 (-) 144 WP_014608661.1 hypothetical protein -
  GFB63_RS02515 (GFB63_02600) - 499116..499346 (-) 231 WP_011226494.1 bacteriocin class II family protein -
  GFB63_RS02520 (GFB63_02605) - 499702..499902 (-) 201 WP_011681569.1 hypothetical protein -
  GFB63_RS02525 (GFB63_02610) - 499921..500097 (-) 177 WP_011681570.1 Blp family class II bacteriocin -
  GFB63_RS02530 (GFB63_02615) - 500348..501085 (+) 738 WP_024010062.1 LytTR family DNA-binding domain-containing protein -
  GFB63_RS10445 comD/blpH 501616..502419 (+) 804 WP_228024405.1 ATP-binding protein Regulator
  GFB63_RS02540 (GFB63_02625) - 502437..502598 (-) 162 WP_011681573.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  GFB63_RS02545 (GFB63_02630) comB 502613..503980 (-) 1368 WP_011681574.1 bacteriocin secretion accessory protein Regulator
  GFB63_RS02550 (GFB63_02635) comA/nlmT 503996..506149 (-) 2154 WP_157795756.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 267 a.a.        Molecular weight: 30694.97 Da        Isoelectric Point: 4.8279

>NTDB_id=345273 GFB63_RS10445 WP_228024405.1 501616..502419(+) (comD/blpH) [Streptococcus thermophilus strain TK-P3A]
MYLENTTHSSTLELRKLCVVISLVLFFIMIVFLDRNIREMIQGQLDFQKNLQLENLYTYNKHIEGLYNSVRSFRHDYSNL
LVTLRLGIDKDDMDIVKEAYDSVLQESDKRLNTRNFDLARLVNIQDNTLKSLLSAKVLQAEEEGIEAQISIPEPIHLIGM
ETLDFIIVTSIFLDNAIEGAIQTQNPKITISFWEDHRSQLLSISNTISEEKTETKTIFERGVSNKGRERGIGLANVTEIL
DNYINVNLETQSNNFSFTQQLTITKKA

Nucleotide


Download         Length: 804 bp        

>NTDB_id=345273 GFB63_RS10445 WP_228024405.1 501616..502419(+) (comD/blpH) [Streptococcus thermophilus strain TK-P3A]
ATGTATCTTGAAAACACTACTCATTCTTCAACTTTGGAGCTTCGAAAACTCTGTGTTGTTATTTCACTTGTCCTCTTCTT
CATTATGATTGTCTTTTTAGACAGAAACATTCGTGAAATGATTCAAGGACAATTGGACTTCCAAAAAAATCTCCAGCTAG
AAAATCTCTACACCTACAATAAACATATTGAAGGTCTCTACAATTCTGTTCGTAGTTTTAGACACGATTATAGTAATCTC
TTAGTCACATTACGATTGGGGATAGATAAAGACGATATGGATATTGTCAAAGAAGCCTATGATAGTGTGCTTCAAGAATC
CGATAAACGATTAAATACAAGAAACTTTGACTTAGCTAGACTCGTTAATATTCAGGATAACACTTTGAAAAGCCTTCTGT
CCGCAAAAGTTCTACAAGCAGAAGAAGAAGGCATTGAAGCTCAGATTAGCATCCCAGAACCCATCCACTTGATTGGGATG
GAGACTCTGGACTTCATTATCGTCACTTCTATTTTTTTAGATAACGCTATTGAAGGTGCCATTCAAACTCAAAACCCTAA
AATTACTATTAGCTTTTGGGAAGATCATCGTTCACAGCTATTATCTATTAGCAATACCATAAGTGAAGAAAAAACAGAAA
CCAAAACCATATTTGAAAGAGGTGTCTCCAACAAGGGACGAGAGCGAGGCATTGGCCTTGCTAATGTCACAGAAATCTTA
GATAACTATATCAATGTAAACTTAGAAACACAGAGTAACAATTTCTCATTCACACAACAATTAACAATAACTAAAAAGGC
CTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(160-263)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.189

95.131

0.363

Multiple sequence alignment