Detailed information NTG0342354

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT47_RS04515
• Genome accession: NZ_CP035452
• Coordinates: 876482..877318 (+)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm123
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 871482..882318

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT47_RS04485 (ETT47_04475)	-	872036..872404 (+)	369	WP_109991961.1	hypothetical protein	-
ETT47_RS04490 (ETT47_04480)	-	872454..873365 (-)	912	WP_109991960.1	diacylglycerol kinase family protein	-
ETT47_RS04495 (ETT47_04485)	-	873482..874132 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT47_RS04500 (ETT47_04490)	-	874129..874569 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT47_RS04505 (ETT47_04495)	ylqF	874788..875636 (+)	849	WP_109991959.1	ribosome biogenesis GTPase YlqF	-
ETT47_RS04510 (ETT47_04500)	-	875626..876417 (+)	792	WP_109991958.1	ribonuclease HII	-
ETT47_RS04515 (ETT47_04505)	dprA	876482..877318 (+)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
ETT47_RS04520 (ETT47_04510)	topA	877427..879556 (+)	2130	WP_109991957.1	type I DNA topoisomerase	-
ETT47_RS04525 (ETT47_04515)	trmFO	879691..881037 (+)	1347	WP_136099061.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=342354 ETT47_RS04515 WP_014407585.1 876482..877318(+) (dprA) [Streptococcus pyogenes strain emm123]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=342354 ETT47_RS04515 WP_014407585.1 876482..877318(+) (dprA) [Streptococcus pyogenes strain emm123]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterProScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367