Detailed information NTG0342192

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT50_RS04650
• Genome accession: NZ_CP035449
• Coordinates: 898753..899589 (-)
• Length: 278 a.a.
• NCBI ID: WP_032465023.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm56
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 893753..904589

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT50_RS04640 (ETT50_04640)	trmFO	895036..896382 (-)	1347	WP_002995015.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ETT50_RS04645 (ETT50_04645)	topA	896517..898646 (-)	2130	WP_063632497.1	type I DNA topoisomerase	-
ETT50_RS04650 (ETT50_04650)	dprA	898753..899589 (-)	837	WP_032465023.1	DNA-processing protein DprA	Machinery gene
ETT50_RS04655 (ETT50_04655)	-	899654..900445 (-)	792	WP_023611055.1	ribonuclease HII	-
ETT50_RS04660 (ETT50_04660)	ylqF	900435..901283 (-)	849	WP_032465022.1	ribosome biogenesis GTPase YlqF	-
ETT50_RS04665 (ETT50_04665)	-	901502..901942 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT50_RS04670 (ETT50_04670)	-	901939..902589 (+)	651	WP_002984629.1	hemolysin III family protein	-
ETT50_RS04675 (ETT50_04675)	-	902706..903617 (+)	912	WP_032465021.1	diacylglycerol kinase family protein	-
ETT50_RS04680 (ETT50_04680)	-	903667..904104 (-)	438	WP_032465020.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31031.01 Da
• Isoelectric Point: 8.8230

>NTDB_id=342192 ETT50_RS04650 WP_032465023.1 898753..899589(-) (dprA) [Streptococcus pyogenes strain emm56]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGFRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=342192 ETT50_RS04650 WP_032465023.1 898753..899589(-) (dprA) [Streptococcus pyogenes strain emm56]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTTCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATACTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363