Detailed information NTG0342136

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT51_RS05230
• Genome accession: NZ_CP035448
• Coordinates: 990929..991765 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm70
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 985929..996765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT51_RS05200 (ETT51_05255)	-	986480..986854 (+)	375	WP_063632495.1	hypothetical protein	-
ETT51_RS05205 (ETT51_05260)	-	986901..987812 (-)	912	WP_023610321.1	diacylglycerol/lipid kinase family protein	-
ETT51_RS05210 (ETT51_05265)	trhA	987929..988579 (-)	651	WP_002984629.1	PAQR family membrane homeostasis protein TrhA	-
ETT51_RS05215 (ETT51_05270)	-	988576..989016 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT51_RS05220 (ETT51_05275)	ylqF	989235..990083 (+)	849	WP_063632496.1	ribosome biogenesis GTPase YlqF	-
ETT51_RS05225 (ETT51_05280)	-	990073..990864 (+)	792	WP_023611055.1	ribonuclease HII	-
ETT51_RS05230 (ETT51_05285)	dprA	990929..991765 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
ETT51_RS05235 (ETT51_05290)	topA	991872..994001 (+)	2130	WP_063632497.1	type I DNA topoisomerase	-
ETT51_RS05240 (ETT51_05295)	trmFO	994136..995482 (+)	1347	WP_002995015.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=342136 ETT51_RS05230 WP_002995009.1 990929..991765(+) (dprA) [Streptococcus pyogenes strain emm70]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=342136 ETT51_RS05230 WP_002995009.1 990929..991765(+) (dprA) [Streptococcus pyogenes strain emm70]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATACTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367