Detailed information NTG0342076

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT52_RS04425
• Genome accession: NZ_CP035447
• Coordinates: 858721..859557 (+)
• Length: 278 a.a.
• NCBI ID: WP_136026141.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm97.1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 853721..864557

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT52_RS04395 (ETT52_04385)	-	854275..854643 (+)	369	WP_010922310.1	hypothetical protein	-
ETT52_RS04400 (ETT52_04390)	-	854693..855604 (-)	912	WP_032460107.1	diacylglycerol kinase family protein	-
ETT52_RS04405 (ETT52_04395)	-	855721..856371 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT52_RS04410 (ETT52_04400)	-	856368..856808 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT52_RS04415 (ETT52_04405)	ylqF	857027..857875 (+)	849	WP_136026143.1	ribosome biogenesis GTPase YlqF	-
ETT52_RS04420 (ETT52_04410)	-	857865..858656 (+)	792	WP_136026142.1	ribonuclease HII	-
ETT52_RS04425 (ETT52_04415)	dprA	858721..859557 (+)	837	WP_136026141.1	DNA-processing protein DprA	Machinery gene
ETT52_RS04430 (ETT52_04420)	topA	859664..861793 (+)	2130	WP_136026140.1	type I DNA topoisomerase	-
ETT52_RS04435 (ETT52_04425)	trmFO	861928..863274 (+)	1347	WP_002995015.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31121.15 Da
• Isoelectric Point: 9.4248

>NTDB_id=342076 ETT52_RS04425 WP_136026141.1 858721..859557(+) (dprA) [Streptococcus pyogenes strain emm97.1]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVFLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=342076 ETT52_RS04425 WP_136026141.1 858721..859557(+) (dprA) [Streptococcus pyogenes strain emm97.1]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCTTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367