Detailed information NTG0342026

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT53_RS04420
• Genome accession: NZ_CP035446
• Coordinates: 860929..861765 (-)
• Length: 278 a.a.
• NCBI ID: WP_020905195.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm68.2
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 855929..866765

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT53_RS04395 (ETT53_04395)	-	856148..857140 (-)	993	WP_129321264.1	D-lactate dehydrogenase	-
ETT53_RS04400 (ETT53_04400)	-	857155..857721 (-)	567	Protein_790	PTS sugar transporter subunit IIC	-
ETT53_RS08780	-	857734..858618 (+)	885	Protein_791	LysR family transcriptional regulator	-
ETT53_RS04415 (ETT53_04415)	topA	858693..860822 (-)	2130	WP_111704647.1	type I DNA topoisomerase	-
ETT53_RS04420 (ETT53_04420)	dprA	860929..861765 (-)	837	WP_020905195.1	DNA-processing protein DprA	Machinery gene
ETT53_RS04425 (ETT53_04425)	-	861830..862621 (-)	792	WP_111704649.1	ribonuclease HII	-
ETT53_RS04430 (ETT53_04430)	ylqF	862611..863459 (-)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
ETT53_RS04435 (ETT53_04435)	-	863678..864118 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT53_RS04440 (ETT53_04440)	-	864115..864765 (+)	651	WP_002984629.1	hemolysin III family protein	-
ETT53_RS04445 (ETT53_04445)	-	864882..865793 (+)	912	WP_111704650.1	diacylglycerol kinase family protein	-
ETT53_RS04450 (ETT53_04450)	-	865843..866283 (-)	441	WP_009880949.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.00 Da
• Isoelectric Point: 9.2514

>NTDB_id=342026 ETT53_RS04420 WP_020905195.1 860929..861765(-) (dprA) [Streptococcus pyogenes strain emm68.2]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=342026 ETT53_RS04420 WP_020905195.1 860929..861765(-) (dprA) [Streptococcus pyogenes strain emm68.2]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAACAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367