Detailed information NTG0341970

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT54_RS04430
• Genome accession: NZ_CP035445
• Coordinates: 869545..870381 (+)
• Length: 278 a.a.
• NCBI ID: WP_111693218.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm92
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 864545..875381

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT54_RS04400 (ETT54_04395)	-	865099..865467 (+)	369	WP_010922310.1	hypothetical protein	-
ETT54_RS04405 (ETT54_04400)	-	865517..866428 (-)	912	WP_136098059.1	diacylglycerol kinase family protein	-
ETT54_RS04410 (ETT54_04405)	-	866545..867195 (-)	651	WP_129321914.1	hemolysin III family protein	-
ETT54_RS04415 (ETT54_04410)	-	867192..867632 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT54_RS04420 (ETT54_04415)	ylqF	867851..868699 (+)	849	WP_136098058.1	ribosome biogenesis GTPase YlqF	-
ETT54_RS04425 (ETT54_04420)	-	868689..869480 (+)	792	WP_011285534.1	ribonuclease HII	-
ETT54_RS04430 (ETT54_04425)	dprA	869545..870381 (+)	837	WP_111693218.1	DNA-processing protein DprA	Machinery gene
ETT54_RS04435 (ETT54_04430)	topA	870488..872617 (+)	2130	WP_115354118.1	type I DNA topoisomerase	-
ETT54_RS08840	-	872693..873550 (-)	858	Protein_816	LysR family transcriptional regulator	-
ETT54_RS04450 (ETT54_04445)	-	873590..874156 (+)	567	Protein_817	PTS sugar transporter subunit IIC	-
ETT54_RS04455 (ETT54_04450)	-	874171..875163 (+)	993	Protein_818	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31073.07 Da
• Isoelectric Point: 9.2565

>NTDB_id=341970 ETT54_RS04430 WP_111693218.1 869545..870381(+) (dprA) [Streptococcus pyogenes strain emm92]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341970 ETT54_RS04430 WP_111693218.1 869545..870381(+) (dprA) [Streptococcus pyogenes strain emm92]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.072	100	0.601
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis SK321	60.072	100	0.601
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.712	100	0.597
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367