Detailed information NTG0341918

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT55_RS04690
• Genome accession: NZ_CP035444
• Coordinates: 905820..906656 (+)
• Length: 278 a.a.
• NCBI ID: WP_002989770.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm90.5
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 900820..911656

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT55_RS04660 (ETT55_04650)	-	901302..901742 (+)	441	WP_024623381.1	hypothetical protein	-
ETT55_RS04665 (ETT55_04655)	-	901792..902703 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
ETT55_RS04670 (ETT55_04660)	-	902820..903470 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT55_RS04675 (ETT55_04665)	-	903467..903907 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT55_RS04680 (ETT55_04670)	ylqF	904126..904974 (+)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
ETT55_RS04685 (ETT55_04675)	-	904964..905755 (+)	792	WP_136021644.1	ribonuclease HII	-
ETT55_RS04690 (ETT55_04680)	dprA	905820..906656 (+)	837	WP_002989770.1	DNA-processing protein DprA	Machinery gene
ETT55_RS04695 (ETT55_04685)	topA	906763..908892 (+)	2130	WP_030125930.1	type I DNA topoisomerase	-
ETT55_RS08825	-	908967..909824 (-)	858	Protein_851	LysR family transcriptional regulator	-
ETT55_RS04710 (ETT55_04700)	-	909864..910430 (+)	567	Protein_852	PTS sugar transporter subunit IIC	-
ETT55_RS04715 (ETT55_04705)	-	910445..911437 (+)	993	WP_002989762.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30956.84 Da
• Isoelectric Point: 8.5841

>NTDB_id=341918 ETT55_RS04690 WP_002989770.1 905820..906656(+) (dprA) [Streptococcus pyogenes strain emm90.5]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341918 ETT55_RS04690 WP_002989770.1 905820..906656(+) (dprA) [Streptococcus pyogenes strain emm90.5]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATAGAATTTAAACAGTTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACGTCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367