Detailed information NTG0341748

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT58_RS04675
• Genome accession: NZ_CP035441
• Coordinates: 897293..898129 (+)
• Length: 278 a.a.
• NCBI ID: WP_010922314.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm1
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 892293..903129

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT58_RS04645 (ETT58_04640)	-	892847..893215 (+)	369	WP_010922310.1	hypothetical protein	-
ETT58_RS04650 (ETT58_04645)	-	893265..894176 (-)	912	WP_010922311.1	diacylglycerol kinase family protein	-
ETT58_RS04655 (ETT58_04650)	-	894293..894943 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT58_RS04660 (ETT58_04655)	-	894940..895380 (-)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT58_RS04665 (ETT58_04660)	ylqF	895599..896447 (+)	849	WP_010922312.1	ribosome biogenesis GTPase YlqF	-
ETT58_RS04670 (ETT58_04665)	-	896437..897228 (+)	792	WP_011285534.1	ribonuclease HII	-
ETT58_RS04675 (ETT58_04670)	dprA	897293..898129 (+)	837	WP_010922314.1	DNA-processing protein DprA	Machinery gene
ETT58_RS04680 (ETT58_04675)	topA	898236..900365 (+)	2130	WP_010922315.1	type I DNA topoisomerase	-
ETT58_RS09525	-	900440..901322 (-)	883	Protein_844	LysR family transcriptional regulator	-
ETT58_RS04695 (ETT58_04690)	-	901335..901880 (+)	546	Protein_845	PTS sugar transporter subunit IIC	-
ETT58_RS04700 (ETT58_04695)	-	901895..902887 (+)	993	WP_010922317.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30973.93 Da
• Isoelectric Point: 9.0514

>NTDB_id=341748 ETT58_RS04675 WP_010922314.1 897293..898129(+) (dprA) [Streptococcus pyogenes strain emm1]
MNHFELYKLKKAGLTNKNILNILDYQKHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQNLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341748 ETT58_RS04675 WP_010922314.1 897293..898129(+) (dprA) [Streptococcus pyogenes strain emm1]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAATTTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367