Detailed information NTG0341542

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT62_RS04370
• Genome accession: NZ_CP035437
• Coordinates: 868436..869272 (-)
• Length: 278 a.a.
• NCBI ID: WP_136120814.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm78.3
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 863436..874272

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT62_RS04345 (ETT62_04345)	-	863675..864667 (-)	993	Protein_774	D-lactate dehydrogenase	-
ETT62_RS04350 (ETT62_04350)	-	864682..865227 (-)	546	Protein_775	PTS sugar transporter subunit IIC	-
ETT62_RS09090	-	865240..866124 (+)	885	Protein_776	LysR family transcriptional regulator	-
ETT62_RS04365 (ETT62_04365)	topA	866199..868328 (-)	2130	WP_136120813.1	type I DNA topoisomerase	-
ETT62_RS04370 (ETT62_04370)	dprA	868436..869272 (-)	837	WP_136120814.1	DNA-processing protein DprA	Machinery gene
ETT62_RS04375 (ETT62_04375)	-	869337..870128 (-)	792	WP_002995007.1	ribonuclease HII	-
ETT62_RS04380 (ETT62_04380)	ylqF	870118..870966 (-)	849	WP_014407584.1	ribosome biogenesis GTPase YlqF	-
ETT62_RS04385 (ETT62_04385)	-	871185..871625 (+)	441	WP_014407583.1	DUF1836 domain-containing protein	-
ETT62_RS04390 (ETT62_04390)	-	871622..872272 (+)	651	WP_002984629.1	hemolysin III family protein	-
ETT62_RS04395 (ETT62_04395)	-	872389..873300 (+)	912	WP_002989777.1	diacylglycerol kinase family protein	-
ETT62_RS04400 (ETT62_04400)	-	873350..873721 (-)	372	WP_014407581.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30989.93 Da
• Isoelectric Point: 8.5827

>NTDB_id=341542 ETT62_RS04370 WP_136120814.1 868436..869272(-) (dprA) [Streptococcus pyogenes strain emm78.3]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGDRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341542 ETT62_RS04370 WP_136120814.1 868436..869272(-) (dprA) [Streptococcus pyogenes strain emm78.3]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGGATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367