Detailed information NTG0341330

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT66_RS04685
• Genome accession: NZ_CP035433
• Coordinates: 931628..932464 (-)
• Length: 278 a.a.
• NCBI ID: WP_136286239.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm65
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 926628..937464

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT66_RS04675 (ETT66_04675)	trmFO	927911..929257 (-)	1347	WP_002995015.1	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	-
ETT66_RS04680 (ETT66_04680)	topA	929392..931521 (-)	2130	WP_136286240.1	type I DNA topoisomerase	-
ETT66_RS04685 (ETT66_04685)	dprA	931628..932464 (-)	837	WP_136286239.1	DNA-processing protein DprA	Machinery gene
ETT66_RS04690 (ETT66_04690)	-	932529..933320 (-)	792	WP_023611055.1	ribonuclease HII	-
ETT66_RS04695 (ETT66_04695)	ylqF	933310..934158 (-)	849	WP_136271686.1	ribosome biogenesis GTPase YlqF	-
ETT66_RS04700 (ETT66_04700)	-	934377..934817 (+)	441	WP_002989774.1	DUF1836 domain-containing protein	-
ETT66_RS04705 (ETT66_04705)	-	934814..935464 (+)	651	WP_002984629.1	hemolysin III family protein	-
ETT66_RS04710 (ETT66_04710)	-	935581..936492 (+)	912	WP_047235287.1	diacylglycerol kinase family protein	-
ETT66_RS04715 (ETT66_04715)	-	936542..936910 (-)	369	WP_010922310.1	hypothetical protein	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31112.14 Da
• Isoelectric Point: 9.4246

>NTDB_id=341330 ETT66_RS04685 WP_136286239.1 931628..932464(-) (dprA) [Streptococcus pyogenes strain emm65]
MNHFELYKLKKAGLTNKNILNILDYQKQQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPREEALSYHFPERNRIIAGLSRGILVVEAKNRSGSFITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341330 ETT66_RS04685 WP_136286239.1 931628..932464(-) (dprA) [Streptococcus pyogenes strain emm65]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAAA
ACAACAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAAGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTTATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	66.906	100	0.669
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae D39	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae R6	59.712	100	0.597
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis SK321	59.712	100	0.597
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	59.353	100	0.594
dprA	Lactococcus lactis subsp. cremoris KW2	56.835	100	0.568
dprA	Legionella pneumophila strain ERS1305867	42.437	85.612	0.363