Detailed information NTG0341274

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT67_RS04720
• Genome accession: NZ_CP035432
• Coordinates: 914593..915429 (+)
• Length: 278 a.a.
• NCBI ID: WP_023079425.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm11
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 909593..920429

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT67_RS04690 (ETT67_04680)	-	910081..910515 (+)	435	WP_023079442.1	hypothetical protein	-
ETT67_RS04695 (ETT67_04685)	-	910565..911476 (-)	912	WP_023079407.1	diacylglycerol kinase family protein	-
ETT67_RS04700 (ETT67_04690)	-	911593..912243 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT67_RS04705 (ETT67_04695)	-	912240..912680 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT67_RS04710 (ETT67_04700)	ylqF	912899..913747 (+)	849	WP_023612970.1	ribosome biogenesis GTPase YlqF	-
ETT67_RS04715 (ETT67_04705)	-	913737..914528 (+)	792	WP_023079417.1	ribonuclease HII	-
ETT67_RS04720 (ETT67_04710)	dprA	914593..915429 (+)	837	WP_023079425.1	DNA-processing protein DprA	Machinery gene
ETT67_RS04725 (ETT67_04715)	topA	915537..917666 (+)	2130	WP_011017773.1	type I DNA topoisomerase	-
ETT67_RS09205	-	917741..918625 (-)	885	Protein_869	LysR family transcriptional regulator	-
ETT67_RS04740 (ETT67_04730)	-	918638..919191 (+)	554	Protein_870	PTS sugar transporter subunit IIC	-
ETT67_RS04745 (ETT67_04735)	-	919206..920198 (+)	993	WP_023078604.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 31046.98 Da
• Isoelectric Point: 8.5827

>NTDB_id=341274 ETT67_RS04720 WP_023079425.1 914593..915429(+) (dprA) [Streptococcus pyogenes strain emm11]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEDR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341274 ETT67_RS04720 WP_023079425.1 914593..915429(+) (dprA) [Streptococcus pyogenes strain emm11]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAACCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGACCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.266	100	0.673
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.432	100	0.604
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis SK321	60.432	100	0.604
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.072	100	0.601
dprA	Lactococcus lactis subsp. cremoris KW2	57.194	100	0.572
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367