Detailed information NTG0341171

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT69_RS05040
• Genome accession: NZ_CP035430
• Coordinates: 955162..955998 (+)
• Length: 278 a.a.
• NCBI ID: WP_014407585.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm55
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 950162..960998

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT69_RS05010 (ETT69_05000)	-	950716..951084 (+)	369	WP_136019413.1	hypothetical protein	-
ETT69_RS05015 (ETT69_05005)	-	951134..952045 (-)	912	WP_002989777.1	diacylglycerol kinase family protein	-
ETT69_RS05020 (ETT69_05010)	-	952162..952812 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT69_RS05025 (ETT69_05015)	-	952809..953249 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT69_RS05030 (ETT69_05020)	ylqF	953468..954316 (+)	849	WP_030125932.1	ribosome biogenesis GTPase YlqF	-
ETT69_RS05035 (ETT69_05025)	-	954306..955097 (+)	792	WP_109991958.1	ribonuclease HII	-
ETT69_RS05040 (ETT69_05030)	dprA	955162..955998 (+)	837	WP_014407585.1	DNA-processing protein DprA	Machinery gene
ETT69_RS05045 (ETT69_05035)	topA	956105..958234 (+)	2130	WP_136019412.1	type I DNA topoisomerase	-
ETT69_RS09765	-	958309..959193 (-)	885	Protein_931	LysR family transcriptional regulator	-
ETT69_RS05060 (ETT69_05050)	-	959206..959772 (+)	567	Protein_932	PTS sugar transporter subunit IIC	-
ETT69_RS05065 (ETT69_05055)	-	959787..960779 (+)	993	WP_136019411.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30988.94 Da
• Isoelectric Point: 8.8230

>NTDB_id=341171 ETT69_RS05040 WP_014407585.1 955162..955998(+) (dprA) [Streptococcus pyogenes strain emm55]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKMEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=341171 ETT69_RS05040 WP_014407585.1 955162..955998(+) (dprA) [Streptococcus pyogenes strain emm55]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCTGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATGGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACTGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACTATC
GCTATTATTGGAACAGGATTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGCCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367