Detailed information NTG0341053

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: ETT71_RS02445
• Genome accession: NZ_CP035428
• Coordinates: 438906..441059 (-)
• Length: 717 a.a.
• NCBI ID: WP_129284363.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emmSTG866.1
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 433906..446059

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT71_RS02415 (ETT71_02415)	-	434146..434368 (+)	223	Protein_420	Blp family class II bacteriocin	-
ETT71_RS02420 (ETT71_02420)	-	434368..434862 (+)	495	Protein_421	transposase	-
ETT71_RS02425 (ETT71_02425)	comE/blpR	435096..435845 (+)	750	WP_030126108.1	response regulator transcription factor	Regulator
ETT71_RS02430 (ETT71_02430)	-	435846..437180 (+)	1335	WP_063631787.1	sensor histidine kinase	-
ETT71_RS02435 (ETT71_02435)	-	437329..437454 (-)	126	WP_011017462.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
ETT71_RS02440 (ETT71_02440)	-	437531..438895 (-)	1365	WP_136046694.1	bacteriocin secretion accessory protein	-
ETT71_RS02445 (ETT71_02445)	comA/nlmT	438906..441059 (-)	2154	WP_129284363.1	peptide cleavage/export ABC transporter	Regulator
ETT71_RS02450 (ETT71_02450)	-	441340..441564 (+)	225	WP_030126106.1	Blp family class II bacteriocin	-
ETT71_RS02455 (ETT71_02455)	-	441641..441859 (+)	219	WP_030126105.1	bacteriocin	-
ETT71_RS02465 (ETT71_02465)	-	442385..442795 (+)	411	WP_003061293.1	hypothetical protein	-
ETT71_RS09415 (ETT71_02470)	-	443037..444106 (+)	1070	Protein_430	hypothetical protein	-
ETT71_RS02475 (ETT71_02475)	-	444199..444597 (+)	399	WP_011054254.1	hypothetical protein	-
ETT71_RS02480 (ETT71_02480)	stcA	444945..445214 (-)	270	WP_136093496.1	quorum-sensing system protein StcA	-
ETT71_RS09160	-	445609..445788 (-)	180	WP_011184266.1	hypothetical protein	-
ETT71_RS09420 (ETT71_02485)	-	445737..445979 (-)	243	WP_002985713.1	hypothetical protein	-

Sequence

Protein

• Length: 717 a.a.
• Molecular weight: 80562.50 Da
• Isoelectric Point: 7.0109

>NTDB_id=341053 ETT71_RS02445 WP_129284363.1 438906..441059(-) (comA/nlmT) [Streptococcus pyogenes strain emmSTG866.1]
MISYRKTFVAQIDARDCGVAALASIAKYYGSDYSLAHLRELAKTNKEGTTALGIVKAAKLMGFETRAIQADMTLFDIEDV
PYPFIVHVNKEGKFQHYYVIYQNKKNYLIIGDPDSTVKVTKMTKERFTSEWTGVAIFLAPEPSYKPHKDKKNGLISFLPL
IFKQRSLIFYIILASLLVTLINIVGSYYLQGILDDYIPNQLKSTLGIISIGLIITYILQQMMSFSRDYLLTVLSQRLSID
VILSYIRHIFELPMSFFATRRTGEIISRFTDANAIIDALASTILSLFLDVSILTIVGTVLLVQNTNLFLLSLVSVPLYIV
IIFIFMHPFEKMNNDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQKIDSEFVDYLDKSFKLSKYSILQSSLKQGAQL
ILNVIVLWFGAKLVMGGKISVGQLITFNTLLSYFTNPLENIINLQTKLQSAKVANNRLNEVYLVDSEFQEAGTLVNQELL
HGDIQFEELSYKYGFGRDTLSNINLTIKQGDKVSLVGISGSGKTTLAKMIVNFFEPYNGRITINHNDLKMIDKKSLRQHI
NYLPQQAYIFNGSILENLTLGANDCTSHEDILRACEVAEIRQDIEQMPMGYQTELSDGAGLSGGQKQRIALARALLTKAP
VLILDEATSGLDVLTEKRVIDNLLAMTDKTIIFVAHRLSISARTNQVIVLDEGKIIEIGSHQELMTKQGFYHHLFSS

Nucleotide

• Length: 2154 bp

>NTDB_id=341053 ETT71_RS02445 WP_129284363.1 438906..441059(-) (comA/nlmT) [Streptococcus pyogenes strain emmSTG866.1]
ATGATATCCTATCGAAAAACATTTGTTGCTCAGATTGATGCTAGAGACTGTGGTGTGGCTGCTCTTGCTTCCATCGCTAA
ATATTACGGTTCAGACTACTCTTTAGCTCATTTAAGAGAGTTAGCTAAAACAAATAAAGAGGGAACAACAGCGCTTGGAA
TCGTCAAAGCTGCCAAATTAATGGGGTTTGAAACAAGAGCTATTCAAGCAGACATGACCCTCTTTGATATAGAAGATGTC
CCTTATCCTTTTATTGTTCATGTTAATAAAGAAGGTAAATTCCAACACTACTATGTCATCTATCAAAACAAAAAAAATTA
TCTGATAATCGGCGACCCTGACTCGACAGTAAAAGTCACTAAGATGACAAAGGAGCGATTTACTTCTGAATGGACGGGTG
TCGCTATTTTTCTAGCACCCGAGCCCAGCTACAAGCCTCATAAGGACAAAAAGAACGGTCTAATAAGCTTTTTACCTCTC
ATTTTTAAACAGCGATCTCTGATTTTCTATATCATATTAGCTAGCCTACTCGTTACTCTGATTAATATTGTAGGTTCTTA
TTACCTACAAGGTATATTAGATGACTATATTCCAAATCAACTGAAATCAACACTCGGCATTATTTCAATTGGTCTTATCA
TTACCTATATCCTCCAACAGATGATGAGTTTTTCGCGAGATTATCTCCTGACTGTACTGAGTCAGCGATTAAGCATTGAT
GTTATTTTATCCTATATTCGTCATATTTTTGAGCTTCCCATGTCTTTCTTTGCAACACGTCGGACAGGAGAAATCATCTC
ACGTTTTACAGATGCTAATGCTATTATTGATGCACTCGCTTCTACTATTTTGTCTCTTTTTCTTGATGTCAGTATTTTAA
CTATCGTAGGGACAGTCCTGTTAGTGCAAAATACCAATCTTTTTCTTCTATCTCTGGTTTCAGTCCCTCTATATATTGTT
ATTATCTTTATATTTATGCACCCATTTGAAAAGATGAATAATGATGTCATGCAGAGTAACTCTATGGTTAGCTCAGCCAT
TATCGAAGATATCAATGGCATTGAAACTATTAAATCACTGACCAGTGAAGAAAATCGTTATCAGAAAATTGATAGTGAAT
TTGTGGACTATCTGGATAAATCCTTCAAGTTAAGTAAGTACTCTATTTTACAAAGCAGTCTCAAACAAGGGGCGCAACTA
ATCCTTAACGTGATAGTCTTATGGTTTGGGGCCAAATTAGTTATGGGAGGAAAAATTTCTGTTGGTCAGTTGATTACGTT
TAATACTCTCTTATCTTATTTTACCAATCCTTTAGAAAATATCATTAATCTTCAAACTAAACTGCAATCAGCCAAGGTAG
CTAATAATCGTCTCAATGAAGTTTACCTAGTCGATTCTGAGTTTCAAGAGGCTGGGACATTAGTCAATCAAGAATTATTA
CACGGAGACATTCAATTTGAAGAGTTATCCTATAAATATGGCTTTGGACGCGATACTCTATCAAATATTAATCTCACTAT
TAAGCAAGGGGACAAAGTTAGCCTTGTTGGTATTAGTGGATCTGGTAAAACGACTCTAGCTAAAATGATTGTTAATTTTT
TTGAGCCTTATAACGGCCGAATTACCATTAATCATAATGACTTAAAAATGATTGATAAAAAAAGTCTTCGCCAACATATT
AATTATCTCCCCCAACAAGCCTATATTTTTAATGGTTCTATTTTAGAAAATTTAACCTTAGGTGCTAATGACTGTACTAG
TCATGAAGATATTCTAAGAGCTTGTGAGGTTGCAGAAATTCGACAAGATATTGAACAAATGCCTATGGGCTATCAAACAG
AGCTTTCTGATGGTGCCGGACTCTCAGGAGGCCAAAAGCAACGAATTGCACTTGCCAGAGCTCTCCTAACCAAGGCGCCT
GTGCTTATTCTAGATGAGGCTACAAGCGGTCTTGACGTACTAACTGAAAAGAGGGTTATTGATAATCTTTTGGCTATGAC
GGATAAAACTATTATTTTCGTAGCTCATCGTCTCAGCATTTCAGCGCGGACCAATCAAGTCATTGTGCTTGATGAGGGTA
AAATTATTGAAATAGGATCTCATCAAGAATTAATGACTAAACAAGGTTTCTATCATCATTTATTTAGTAGTTAA

Domains

Predicted by InterproScan.

• ABC transporter transmembrane region (ABC_membrane) (168-438)

• ABC transporter (ABC_tran) (500-649)

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.587	99.721	0.724
comA	Streptococcus mitis NCTC 12261	67.367	99.582	0.671
comA	Streptococcus mitis SK321	66.947	99.582	0.667
comA	Streptococcus pneumoniae Rx1	66.947	99.582	0.667
comA	Streptococcus pneumoniae D39	66.947	99.582	0.667
comA	Streptococcus pneumoniae R6	66.947	99.582	0.667
comA	Streptococcus pneumoniae TIGR4	66.667	99.582	0.664
comA	Streptococcus gordonii str. Challis substr. CH1	65.738	100	0.658