Detailed information NTG0340951

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: ETT73_RS04575
• Genome accession: NZ_CP035426
• Coordinates: 880747..881583 (+)
• Length: 278 a.a.
• NCBI ID: WP_002995009.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain emm57
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 875747..886583

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ETT73_RS04545 (ETT73_04540)	-	876295..876669 (+)	375	WP_136276661.1	hypothetical protein	-
ETT73_RS04550 (ETT73_04545)	-	876719..877630 (-)	912	WP_136276660.1	diacylglycerol kinase family protein	-
ETT73_RS04555 (ETT73_04550)	-	877747..878397 (-)	651	WP_002984629.1	hemolysin III family protein	-
ETT73_RS04560 (ETT73_04555)	-	878394..878834 (-)	441	WP_011017769.1	DUF1836 domain-containing protein	-
ETT73_RS04565 (ETT73_04560)	ylqF	879053..879901 (+)	849	WP_032460105.1	ribosome biogenesis GTPase YlqF	-
ETT73_RS04570 (ETT73_04565)	-	879891..880682 (+)	792	WP_011888871.1	ribonuclease HII	-
ETT73_RS04575 (ETT73_04570)	dprA	880747..881583 (+)	837	WP_002995009.1	DNA-processing protein DprA	Machinery gene
ETT73_RS04580 (ETT73_04575)	topA	881690..883819 (+)	2130	WP_136112553.1	type I DNA topoisomerase	-
ETT73_RS08910	-	883895..884752 (-)	858	Protein_818	LysR family transcriptional regulator	-
ETT73_RS04595 (ETT73_04590)	-	884792..885358 (+)	567	Protein_819	PTS sugar transporter subunit IIC	-
ETT73_RS04600 (ETT73_04595)	-	885373..886365 (+)	993	WP_136276659.1	D-lactate dehydrogenase	-

Sequence

Protein

• Length: 278 a.a.
• Molecular weight: 30970.91 Da
• Isoelectric Point: 8.8230

>NTDB_id=340951 ETT73_RS04575 WP_002995009.1 880747..881583(+) (dprA) [Streptococcus pyogenes strain emm57]
MNHFELYKLKKAGLTNKNILNILDYQEHQEKSLSLRDMAVVSGCKHPSHFIEAYKQLDIQKLKIEFKQFPSISILDKHYP
MALKEIYNPPVLLFFQGNLDLLEKPKLAIVGSRRSSDTGVKSVRKILKELGNRFVIVSGLARGIDTSAHLACLKNGGQTI
AIIGTGLDRFYPKENRELQTFLGKNHLVLTEYGPGEEALSYHFPERNRIIAGLSRGILVVEAKNRSGSLITCQIGIEEGR
DIFAVPGNILDGKSEGCLQLIKEGATCVTSGMDILSEY

Nucleotide

• Length: 837 bp

>NTDB_id=340951 ETT73_RS04575 WP_002995009.1 880747..881583(+) (dprA) [Streptococcus pyogenes strain emm57]
GTGAATCATTTTGAACTTTATAAGCTAAAGAAAGCTGGACTGACTAATAAAAACATTCTCAATATTCTTGACTACCAAGA
ACACCAGGAAAAATCGTTGTCACTTCGAGATATGGCCGTTGTTTCTGGTTGTAAGCATCCGTCTCACTTTATAGAAGCCT
ATAAGCAGTTAGATATTCAAAAATTAAAAATAGAATTTAAACAATTTCCTAGTATTTCTATCTTAGATAAGCATTACCCA
ATGGCATTGAAAGAAATATACAATCCACCTGTCCTCTTGTTTTTTCAGGGAAATTTAGACCTTCTTGAGAAACCTAAATT
AGCCATTGTCGGCTCCAGACGCTCAAGCGATACCGGAGTAAAGTCTGTCCGTAAAATTCTTAAAGAACTCGGGAATCGTT
TTGTGATTGTTAGCGGACTTGCTCGAGGTATCGACACTAGTGCTCATTTAGCCTGCCTTAAAAATGGGGGACAAACCATC
GCTATTATTGGAACAGGGTTGGATCGCTTTTACCCTAAAGAAAATAGGGAGTTGCAAACTTTCTTAGGGAAAAATCATCT
TGTGCTAACAGAATACGGTCCAGGAGAAGAAGCTTTATCTTATCACTTTCCAGAACGGAATCGTATTATCGCAGGTCTTA
GCCGAGGTATTCTTGTCGTTGAAGCAAAAAATCGTTCAGGTTCCTTGATTACTTGTCAAATTGGGATAGAAGAAGGCCGA
GACATTTTTGCTGTCCCAGGAAACATTTTGGACGGGAAATCCGAAGGTTGCCTTCAGTTAATTAAAGAGGGAGCAACATG
CGTCACATCGGGCATGGATATCCTTTCAGAGTACTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (1-62)

• DNA recombination-mediator protein A (DNA_processg_A) (68-269)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Streptococcus mutans UA159	67.626	100	0.676
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae D39	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae R6	60.791	100	0.608
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis SK321	60.791	100	0.608
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	60.432	100	0.604
dprA	Lactococcus lactis subsp. cremoris KW2	57.554	100	0.576
dprA	Legionella pneumophila strain ERS1305867	42.857	85.612	0.367