Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   ERO09_RS00405 Genome accession   NZ_CP035368
Coordinates   83457..84842 (+) Length   461 a.a.
NCBI ID   WP_128786784.1    Uniprot ID   -
Organism   Haemophilus parainfluenzae strain LC_1315_18     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 78457..89842
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ERO09_RS00380 (ERO09_00385) - 78468..81086 (-) 2619 WP_126470285.1 penicillin-binding protein 1A -
  ERO09_RS00385 (ERO09_00390) - 81186..82028 (+) 843 WP_049357171.1 pilus assembly protein PilM -
  ERO09_RS00390 (ERO09_00395) - 82021..82533 (+) 513 WP_128786782.1 competence protein ComB -
  ERO09_RS00395 (ERO09_00400) - 82605..83072 (+) 468 WP_253257859.1 competence protein ComC -
  ERO09_RS00400 (ERO09_00405) - 83072..83455 (+) 384 WP_128786783.1 pilus assembly protein PilP -
  ERO09_RS00405 (ERO09_00410) comE 83457..84842 (+) 1386 WP_128786784.1 type IV pilus secretin PilQ Machinery gene
  ERO09_RS00410 (ERO09_00415) - 84862..85551 (+) 690 WP_049357180.1 ComF family protein -
  ERO09_RS00415 (ERO09_00420) nfuA 85665..86249 (+) 585 WP_005694707.1 Fe-S biogenesis protein NfuA -
  ERO09_RS00420 (ERO09_00425) comM 86293..87822 (-) 1530 WP_128786785.1 YifB family Mg chelatase-like AAA ATPase Machinery gene
  ERO09_RS00425 (ERO09_00430) yihA 87952..88566 (-) 615 WP_049357183.1 ribosome biogenesis GTP-binding protein YihA/YsxC -

Sequence

Protein


Download         Length: 461 a.a.        Molecular weight: 51350.98 Da        Isoelectric Point: 7.5108

>NTDB_id=339331 ERO09_RS00405 WP_128786784.1 83457..84842(+) (comE) [Haemophilus parainfluenzae strain LC_1315_18]
MIKQKIKTKCGQFLMCFLILWTTYSSAENRVFSLRLKQAPMVATLQQLALEQNANLMIDDELEGTLSLQLENVDFDRLLR
SVAKIKRLSFYQENDIYYLGKPSQHEQYAEKMTEPMAISGESLPSETPLVSTTVKLHFAKASDVMKSLTTGSGSLLSPSG
TITFDDRSNVLLIQDDARSIKNIKKLIAELDKPIEQIVIEARIVTITDESLKELGVRWGIFNPTETAHRVSGSLDANGFS
NISNNLNVNFATTVTPAGSLAFQVAKINGRLLDLELTALERENNVEIIASPRLLTTNKKSASIKQGTEIPYVVTNGKNDT
QSVEFREAVLGLEVTPHISKDNNILLDLLVSQNSPGNRVAYGQGNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKG
IDKVPLLGDIPGIKRLFSKESERHQKRELVIFVTPHILKQGERMEMAKKEKHFKQIEKAKK

Nucleotide


Download         Length: 1386 bp        

>NTDB_id=339331 ERO09_RS00405 WP_128786784.1 83457..84842(+) (comE) [Haemophilus parainfluenzae strain LC_1315_18]
ATGATAAAGCAGAAAATAAAAACAAAGTGCGGTCAGTTTTTAATGTGTTTTTTGATCCTATGGACAACTTACTCATCGGC
AGAAAATCGCGTATTTTCACTTCGCTTAAAACAAGCTCCCATGGTGGCGACACTCCAGCAACTTGCTCTTGAGCAAAATG
CCAATTTAATGATTGATGATGAGTTAGAAGGAACGCTTTCATTGCAATTAGAGAACGTAGATTTTGATCGTTTATTGCGT
TCTGTGGCAAAAATCAAAAGGCTCTCTTTTTATCAAGAAAATGATATTTATTATTTGGGTAAGCCTTCTCAACATGAACA
ATATGCAGAGAAAATGACAGAACCTATGGCGATTAGCGGAGAAAGTTTGCCTAGTGAAACACCACTTGTGAGTACAACGG
TTAAACTGCATTTTGCTAAGGCCTCTGATGTGATGAAATCTTTAACAACTGGTAGTGGTTCTTTGCTTTCACCTAGCGGC
ACAATTACCTTTGATGATCGAAGCAATGTGTTACTGATTCAGGATGATGCACGTTCTATCAAAAATATCAAAAAATTAAT
TGCAGAGCTGGATAAACCCATTGAACAAATTGTCATTGAAGCACGTATAGTGACGATTACTGATGAAAGCCTGAAAGAAT
TAGGTGTGCGTTGGGGCATTTTTAATCCCACTGAAACTGCCCATCGAGTGAGTGGCAGTTTAGATGCGAATGGCTTTAGT
AATATCAGTAATAATTTAAATGTTAATTTTGCGACAACGGTCACGCCAGCTGGCTCATTAGCATTTCAAGTCGCTAAAAT
TAATGGCCGATTATTAGACTTAGAATTGACTGCACTTGAACGTGAAAATAACGTAGAAATTATTGCGAGCCCTCGCTTAC
TCACGACCAATAAGAAAAGTGCAAGTATCAAACAAGGGACGGAAATTCCTTATGTAGTGACGAACGGGAAAAATGACACC
CAATCAGTGGAGTTTCGAGAAGCTGTGTTGGGATTGGAAGTCACACCGCATATTTCAAAGGATAATAATATCTTATTGGA
TTTATTAGTCAGTCAAAATTCCCCGGGAAACCGTGTGGCTTACGGGCAAGGTAACGAAGTCGTGTCTATTGATAAACAAG
AAATTAATACGCAAGTTTTTGCTAAAGATGGGGAAACGATTGTATTAGGTGGTGTATTCCACGATACGATCACAAAAGGA
ATTGATAAAGTGCCGCTATTGGGTGATATTCCAGGTATTAAGCGCTTATTTAGTAAGGAAAGTGAACGTCATCAAAAGCG
AGAGCTTGTAATTTTTGTGACTCCTCATATTTTAAAACAAGGTGAAAGAATGGAAATGGCTAAGAAAGAAAAGCATTTTA
AGCAAATTGAAAAAGCGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II and III secretion system protein (Secretin)

(278-439)

Bacterial type II/III secretion system short domain (Secretin_N)

(133-196)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

73.111

97.614

0.714
  comE Haemophilus influenzae 86-028NP

72.222

97.614

0.705
  comE Glaesserella parasuis strain SC1401

54.009

91.974

0.497
  pilQ Vibrio campbellii strain DS40M4

41.339

93.926

0.388
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

41.647

92.191

0.384
  pilQ Vibrio cholerae strain A1552

41.647

92.191

0.384

Multiple sequence alignment