Detailed information NTG0338687

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EQH15_RS04525
• Genome accession: NZ_CP035265
• Coordinates: 886393..887043 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387345.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901920
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 881393..892043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH15_RS04495 (EQH15_04735)	-	881876..882091 (+)	216	WP_001232082.1	YozE family protein	-
EQH15_RS04500 (EQH15_04740)	-	882177..883145 (+)	969	WP_000658183.1	PhoH family protein	-
EQH15_RS04505 (EQH15_04750)	-	883338..883838 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH15_RS04510 (EQH15_04755)	-	883841..884167 (+)	327	Protein_899	TfoX/Sxy family protein	-
EQH15_RS04515 (EQH15_04760)	ald	884468..885579 (-)	1112	Protein_900	alanine dehydrogenase	-
EQH15_RS04520 (EQH15_04765)	-	885756..886325 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
EQH15_RS04525 (EQH15_04770)	comEA/celA/cilE	886393..887043 (+)	651	WP_000387345.1	helix-hairpin-helix domain-containing protein	Machinery gene
EQH15_RS04530 (EQH15_04775)	comEC/celB	887027..889267 (+)	2241	WP_000942434.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH15_RS04535 (EQH15_04780)	-	889466..889654 (+)	189	WP_001812421.1	hypothetical protein	-
EQH15_RS04540 (EQH15_04785)	-	889687..890274 (+)	588	WP_000939895.1	ATP-binding cassette domain-containing protein	-
EQH15_RS04545 (EQH15_04790)	-	890278..891459 (+)	1182	WP_000655932.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23198.46 Da
• Isoelectric Point: 5.5171

>NTDB_id=338687 EQH15_RS04525 WP_000387345.1 886393..887043(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901920]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKTVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=338687 EQH15_RS04525 WP_000387345.1 886393..887043(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901920]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGAAAAGGAAGTGAAGAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAAGGACTGGGAGGAAAACGTGCTCAGGATATTATCGACCATCGTGAAACAAATGG
CAAGTTCAAGTCAGTAGACGAACTCAAGACAGTCTCTGGCATTGGTGCTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.611	100	0.986
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	95.833	100	0.958
comEA/celA/cilE	Streptococcus pneumoniae R6	95.833	100	0.958
comEA/celA/cilE	Streptococcus pneumoniae Rx1	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	41.333	100	0.431
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366