Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH15_RS02600 Genome accession   NZ_CP035265
Coordinates   503856..505532 (-) Length   558 a.a.
NCBI ID   WP_306423909.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901920     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 498856..510532
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH15_RS02570 (EQH15_02695) - 499190..499519 (-) 330 WP_000132572.1 hypothetical protein -
  EQH15_RS02575 (EQH15_02700) - 499796..500134 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  EQH15_RS02580 (EQH15_02705) comE/blpR 500139..500876 (+) 738 WP_001219126.1 response regulator transcription factor Regulator
  EQH15_RS02585 (EQH15_02710) - 500890..502230 (+) 1341 WP_001017622.1 sensor histidine kinase -
  EQH15_RS02590 (EQH15_02715) blpC 502272..502427 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  EQH15_RS02595 (EQH15_02720) - 502484..503845 (-) 1362 Protein_512 bacteriocin secretion accessory protein -
  EQH15_RS02600 (EQH15_02725) comA/nlmT 503856..505532 (-) 1677 WP_306423909.1 peptide cleavage/export ABC transporter Regulator
  EQH15_RS10895 comA/nlmT 505426..506013 (-) 588 WP_001855030.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH15_RS02605 (EQH15_02730) - 506303..506506 (+) 204 WP_001093272.1 bacteriocin class II family protein -
  EQH15_RS02610 (EQH15_02735) - 506824..507027 (+) 204 WP_000411016.1 hypothetical protein -
  EQH15_RS10805 (EQH15_02745) - 508030..508829 (+) 800 Protein_517 IS5 family transposase -
  EQH15_RS02625 (EQH15_02750) blpM 508982..509236 (+) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  EQH15_RS02630 (EQH15_02755) blpN 509252..509455 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  EQH15_RS02635 (EQH15_02765) - 509699..509932 (+) 234 WP_000379963.1 hypothetical protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62978.29 Da        Isoelectric Point: 7.1280

>NTDB_id=338680 EQH15_RS02600 WP_306423909.1 503856..505532(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901920]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=338680 EQH15_RS02600 WP_306423909.1 503856..505532(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901920]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAGTACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667

Multiple sequence alignment