Detailed information NTG0338610

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: EQH16_RS04790
• Genome accession: NZ_CP035264
• Coordinates: 921101..921751 (+)
• Length: 216 a.a.
• NCBI ID: WP_000387345.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901921
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 916101..926751

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH16_RS04760 (EQH16_04990)	-	916584..916799 (+)	216	WP_001232082.1	YozE family protein	-
EQH16_RS04765 (EQH16_04995)	-	916885..917853 (+)	969	WP_000658183.1	PhoH family protein	-
EQH16_RS04770 (EQH16_05005)	-	918046..918546 (+)	501	WP_000566988.1	GNAT family N-acetyltransferase	-
EQH16_RS04775 (EQH16_05010)	-	918549..918875 (+)	327	Protein_953	TfoX/Sxy family protein	-
EQH16_RS04780 (EQH16_05015)	ald	919176..920287 (-)	1112	Protein_954	alanine dehydrogenase	-
EQH16_RS04785 (EQH16_05020)	-	920464..921033 (+)	570	WP_000443775.1	GNAT family N-acetyltransferase	-
EQH16_RS04790 (EQH16_05025)	comEA/celA/cilE	921101..921751 (+)	651	WP_000387345.1	helix-hairpin-helix domain-containing protein	Machinery gene
EQH16_RS04795 (EQH16_05030)	comEC/celB	921735..923975 (+)	2241	WP_000942434.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
EQH16_RS04800 (EQH16_05035)	-	924164..924352 (+)	189	WP_001812421.1	hypothetical protein	-
EQH16_RS04805 (EQH16_05040)	-	924385..924972 (+)	588	WP_000939895.1	ATP-binding cassette domain-containing protein	-
EQH16_RS04810 (EQH16_05045)	-	924976..926157 (+)	1182	WP_000655932.1	membrane protein	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23198.46 Da
• Isoelectric Point: 5.5171

>NTDB_id=338610 EQH16_RS04790 WP_000387345.1 921101..921751(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901921]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDSSTEKEVKKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGSGTASSTSKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHRETNGKFKSVDELKTVSGIGAKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=338610 EQH16_RS04790 WP_000387345.1 921101..921751(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain TVO_1901921]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTTGCAGCTGTTTCCAAGGACT
CATCGACCGAAAAGGAAGTGAAGAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGTCAACAGACTGGTTCGGGGACAGCTTCTTCAACAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAAGGACTGGGAGGAAAACGTGCTCAGGATATTATCGACCATCGTGAAACAAATGG
CAAGTTCAAGTCAGTAGACGAACTCAAGACAGTCTCTGGCATTGGTGCTAAGACCATAGAAAAGCTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (151-214)

• SLBB domain (SLBB) (76-126)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	98.611	100	0.986
comEA/celA/cilE	Streptococcus mitis NCTC 12261	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	95.833	100	0.958
comEA/celA/cilE	Streptococcus pneumoniae R6	95.833	100	0.958
comEA/celA/cilE	Streptococcus pneumoniae Rx1	95.833	100	0.958
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	41.333	100	0.431
comEA	Latilactobacillus sakei subsp. sakei 23K	33.906	100	0.366