Detailed information NTG0338569

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: EQH17_RS09525
• Genome accession: NZ_CP035263
• Coordinates: 1897982..1898443 (-)
• Length: 153 a.a.
• NCBI ID: WP_000250529.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901922
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1892982..1903443

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH17_RS09495 (EQH17_10055)	-	1893294..1894118 (-)	825	WP_000727904.1	membrane protein insertase YidC	-
EQH17_RS09500 (EQH17_10060)	rnpA	1894093..1894464 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH17_RS09505 (EQH17_10065)	-	1894612..1895802 (-)	1191	WP_000167755.1	acetate kinase	-
EQH17_RS09510 (EQH17_10070)	comYH	1895853..1896806 (-)	954	WP_000345084.1	class I SAM-dependent methyltransferase	Machinery gene
EQH17_RS09515 (EQH17_10075)	-	1896867..1897454 (-)	588	Protein_1872	class I SAM-dependent methyltransferase	-
EQH17_RS09520 (EQH17_10080)	comGG/cglG	1897591..1898004 (-)	414	WP_000265617.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH17_RS09525 (EQH17_10085)	comGF/cglF	1897982..1898443 (-)	462	WP_000250529.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH17_RS09530 (EQH17_10090)	comGE/cglE	1898406..1898708 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH17_RS09535 (EQH17_10095)	comGD/cglD	1898671..1899075 (-)	405	WP_000588002.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH17_RS09540 (EQH17_10100)	comGC/cglC	1899068..1899334 (-)	267	WP_000962026.1	competence type IV pilus major pilin ComGC	Machinery gene
EQH17_RS09545 (EQH17_10105)	-	1899336..1899593 (-)	258	WP_000698511.1	hypothetical protein	-
EQH17_RS09550 (EQH17_10110)	lytA	1899825..1900781 (-)	957	WP_061632303.1	N-acetylmuramoyl-L-alanine amidase LytA	-
EQH17_RS09555 (EQH17_10115)	-	1900785..1901117 (-)	333	WP_061632304.1	phage holin	-
EQH17_RS09560 (EQH17_10120)	-	1901121..1901537 (-)	417	WP_001165341.1	phage holin family protein	-
EQH17_RS09565 (EQH17_10125)	-	1901547..1901897 (-)	351	WP_000852244.1	hypothetical protein	-
EQH17_RS09570 (EQH17_10130)	-	1901900..1902103 (-)	204	WP_001091119.1	hypothetical protein	-
EQH17_RS11115 (EQH17_10135)	-	1902084..1902201 (-)	118	Protein_1884	dihydrodipicolinate reductase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17851.34 Da
• Isoelectric Point: 6.4832

>NTDB_id=338569 EQH17_RS09525 WP_000250529.1 1897982..1898443(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901922]
MVQNSCWQSKSHKVKAFTLLESLLALIVISGGLLLFQAMSQLLISEVRYQQQSEQKEWLLFVDQLEAELDRSQFEKVESN
RLYMKQDGKDIAIGKSKSDDFRKTDASGRGYQPMVYGLKSAQITEDNQLVHFRFQFQKGLEREFIYRVEKEES

Nucleotide

• Length: 462 bp

>NTDB_id=338569 EQH17_RS09525 WP_000250529.1 1897982..1898443(-) (comGF/cglF) [Streptococcus pneumoniae strain TVO_1901922]
ATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAAGGTCAAGGCTTTTACCTTGTTAGAATCCCTGCTTGCCCTCAT
TGTCATCAGTGGGGGATTACTCCTTTTTCAAGCTATGAGTCAGCTCCTCATTTCAGAAGTTCGCTACCAGCAACAAAGCG
AGCAAAAGGAGTGGCTCTTGTTTGTGGACCAACTTGAGGCAGAATTAGACCGTTCGCAGTTCGAAAAAGTAGAAAGCAAT
CGCCTATACATGAAGCAAGATGGCAAGGACATCGCCATCGGTAAGTCAAAGTCAGACGATTTTCGTAAAACCGATGCTAG
TGGACGGGGGTATCAGCCTATGGTTTATGGCCTCAAATCAGCTCAGATTACAGAGGACAATCAACTGGTTCATTTTCGTT
TCCAGTTTCAAAAAGGCTTAGAAAGGGAGTTCATCTATCGTGTGGAAAAAGAAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (45-141)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae Rx1	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae D39	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae R6	94.118	100	0.941
comGF/cglF	Streptococcus pneumoniae TIGR4	94.118	100	0.941
comGF/cglF	Streptococcus mitis SK321	92.81	100	0.928
comGF/cglF	Streptococcus mitis NCTC 12261	91.503	100	0.915