Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   EQH18_RS09605 Genome accession   NZ_CP035262
Coordinates   1906726..1907742 (-) Length   338 a.a.
NCBI ID   WP_077141332.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901923     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1901726..1912742
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH18_RS09565 (EQH18_10095) - 1901942..1903132 (-) 1191 WP_000167755.1 acetate kinase -
  EQH18_RS09570 (EQH18_10100) comYH 1903183..1904136 (-) 954 WP_000345084.1 class I SAM-dependent methyltransferase Machinery gene
  EQH18_RS09575 (EQH18_10105) - 1904197..1904784 (-) 588 Protein_1884 class I SAM-dependent methyltransferase -
  EQH18_RS09580 (EQH18_10110) comGG/cglG 1904921..1905334 (-) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH18_RS09585 (EQH18_10115) comGF/cglF 1905312..1905773 (-) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH18_RS09590 (EQH18_10120) comGE/cglE 1905736..1906038 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH18_RS09595 (EQH18_10125) comGD/cglD 1906001..1906405 (-) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH18_RS09600 (EQH18_10130) comGC/cglC 1906398..1906724 (-) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  EQH18_RS09605 (EQH18_10135) comGB/cglB 1906726..1907742 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH18_RS09610 (EQH18_10140) comGA/cglA/cilD 1907690..1908631 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH18_RS09615 (EQH18_10145) - 1908707..1909072 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH18_RS09620 (EQH18_10150) - 1909223..1910281 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH18_RS09625 (EQH18_10155) nagA 1910444..1911595 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38466.48 Da        Isoelectric Point: 9.6162

>NTDB_id=338496 EQH18_RS09605 WP_077141332.1 1906726..1907742(-) (comGB/cglB) [Streptococcus pneumoniae strain TVO_1901923]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRTGLSQGKSFSEMMESLGCSSTI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLGFLLLIMLGLRNYLLPQLDSSNIATRIIGNLPQIF
LGMVGLVSVLALLALTFYKRSSKMSVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=338496 EQH18_RS09605 WP_077141332.1 1906726..1907742(-) (comGB/cglB) [Streptococcus pneumoniae strain TVO_1901923]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACCATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTACAGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTACCATT
GTCACTCAGTTATCTCTAGCTGAAGTTCATGGCAATCTTCACCTGAGTTTGGGAAAGATAGAAGAATATCTAGACAATCT
GGCCAAGGTCAAGAAAAAGTTAATTGAAGTAGCGACCTATCCTTTGATTTTGCTGGGTTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCGAATTATCGGTAATCTGCCACAAATTTTT
CTAGGCATGGTAGGGCTTGTTTCCGTGCTTGCCCTTTTAGCACTAACTTTTTATAAAAGAAGTTCTAAGATGAGTGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTACTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGCTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTTATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCCATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae D39

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae R6

98.817

100

0.988
  comGB/cglB Streptococcus pneumoniae TIGR4

98.817

100

0.988
  comGB/cglB Streptococcus mitis SK321

95.266

100

0.953
  comGB/cglB Streptococcus mitis NCTC 12261

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.833

99.408

0.704
  comYB Streptococcus mutans UA140

58.176

94.083

0.547
  comYB Streptococcus mutans UA159

58.176

94.083

0.547
  comGB Lactococcus lactis subsp. cremoris KW2

50.898

98.817

0.503

Multiple sequence alignment