Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   EQH18_RS09590 Genome accession   NZ_CP035262
Coordinates   1905736..1906038 (-) Length   100 a.a.
NCBI ID   WP_000413382.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901923     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1900736..1911038
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH18_RS09560 (EQH18_10090) rnpA 1901423..1901794 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH18_RS09565 (EQH18_10095) - 1901942..1903132 (-) 1191 WP_000167755.1 acetate kinase -
  EQH18_RS09570 (EQH18_10100) comYH 1903183..1904136 (-) 954 WP_000345084.1 class I SAM-dependent methyltransferase Machinery gene
  EQH18_RS09575 (EQH18_10105) - 1904197..1904784 (-) 588 Protein_1884 class I SAM-dependent methyltransferase -
  EQH18_RS09580 (EQH18_10110) comGG/cglG 1904921..1905334 (-) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH18_RS09585 (EQH18_10115) comGF/cglF 1905312..1905773 (-) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH18_RS09590 (EQH18_10120) comGE/cglE 1905736..1906038 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH18_RS09595 (EQH18_10125) comGD/cglD 1906001..1906405 (-) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH18_RS09600 (EQH18_10130) comGC/cglC 1906398..1906724 (-) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  EQH18_RS09605 (EQH18_10135) comGB/cglB 1906726..1907742 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH18_RS09610 (EQH18_10140) comGA/cglA/cilD 1907690..1908631 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH18_RS09615 (EQH18_10145) - 1908707..1909072 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH18_RS09620 (EQH18_10150) - 1909223..1910281 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11108.08 Da        Isoelectric Point: 9.7273

>NTDB_id=338493 EQH18_RS09590 WP_000413382.1 1905736..1906038(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901923]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=338493 EQH18_RS09590 WP_000413382.1 1905736..1906038(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901923]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

100

100

1
  comGE/cglE Streptococcus pneumoniae D39

100

100

1
  comGE/cglE Streptococcus pneumoniae R6

100

100

1
  comGE/cglE Streptococcus pneumoniae TIGR4

100

100

1
  comGE/cglE Streptococcus mitis NCTC 12261

98

100

0.98
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4

Multiple sequence alignment