Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB   Type   Regulator
Locus tag   EQH18_RS00230 Genome accession   NZ_CP035262
Coordinates   44294..45643 (+) Length   449 a.a.
NCBI ID   WP_000801611.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901923     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 39294..50643
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH18_RS00205 (EQH18_00210) plsX 39413..40405 (+) 993 WP_000717456.1 phosphate acyltransferase PlsX -
  EQH18_RS00210 (EQH18_00215) - 40411..40644 (+) 234 WP_000136449.1 acyl carrier protein -
  EQH18_RS00215 (EQH18_00220) - 40681..40981 (+) 301 Protein_36 transposase family protein -
  EQH18_RS00220 (EQH18_00225) blpU 41183..41413 (+) 231 WP_001093075.1 bacteriocin-like peptide BlpU -
  EQH18_RS10635 - 41416..41541 (+) 126 WP_000346297.1 PncF family bacteriocin immunity protein -
  EQH18_RS00225 (EQH18_00230) comA 42128..44281 (+) 2154 WP_000668272.1 peptide cleavage/export ABC transporter ComA Regulator
  EQH18_RS00230 (EQH18_00235) comB 44294..45643 (+) 1350 WP_000801611.1 competence pheromone export protein ComB Regulator
  EQH18_RS00235 (EQH18_00240) purC 45813..46520 (+) 708 WP_000043309.1 phosphoribosylaminoimidazolesuccinocarboxamide synthase -
  EQH18_RS10715 (EQH18_00245) - 46522..46665 (+) 144 WP_050167432.1 hypothetical protein -
  EQH18_RS00240 (EQH18_00250) - 46722..50447 (+) 3726 WP_000361173.1 phosphoribosylformylglycinamidine synthase -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 49601.49 Da        Isoelectric Point: 5.5642

>NTDB_id=338437 EQH18_RS00230 WP_000801611.1 44294..45643(+) (comB) [Streptococcus pneumoniae strain TVO_1901923]
MKPEFLESAEFYNRRYHNFSSSVIVPMALLLVFLLGFATVAEKEMSLSTRATVEPSRILANIQSTSNNRILVNHLEENKL
VKKGDLLVQYQEGAEGVQAESYASQLDMLKDQKKQLEYLQKSLQEGENHFPEEDKFGYQATFRDYISQAGSLRASTSQQN
ETIASQNAAASQTQAEIGNLISQTEAKIRDYQTAKSAIETGASLAGQNLAYSLYQSYKSQGEENPQTKVQAVAQVEAQIS
QLESSLATYRVQYAGSGTQQAYASGLSSQLESLKSQHLAKVGQELTLLAQKILEAESGKKVQGNLLDKGKVTASEDGVLH
LNPETSDSSMVAEGALLAQLYPSLEREGKAKLTAYLSSKYVARIKVGDSVRYTTTHDAGNQLFLDSTITSIDATATKTEK
GNFFKIEAETNLTSEQAEKLRYGVEGRLQMITGKKSYLRYYLDQFLNKE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=338437 EQH18_RS00230 WP_000801611.1 44294..45643(+) (comB) [Streptococcus pneumoniae strain TVO_1901923]
ATGAAACCAGAATTTTTAGAAAGTGCGGAGTTTTATAATCGTCGTTACCATAATTTTTCCAGTAGTGTGATTGTACCCAT
GGCCCTTCTGCTTGTGTTTTTACTTGGCTTTGCAACTGTTGCAGAGAAGGAGATGAGTTTGTCCACTAGAGCTACTGTCG
AACCTAGTCGTATCCTTGCAAATATCCAGTCAACTAGCAACAATCGTATTCTTGTCAATCATTTGGAAGAAAATAAGCTG
GTTAAGAAGGGGGATCTTTTGGTTCAATACCAAGAAGGGGCAGAGGGTGTCCAAGCGGAGTCCTATGCCAGTCAGTTGGA
CATGCTAAAGGATCAAAAAAAGCAATTGGAGTATCTGCAAAAGAGCCTGCAAGAAGGGGAGAACCACTTTCCAGAGGAGG
ATAAGTTTGGCTACCAAGCCACCTTTCGCGACTACATCAGTCAAGCAGGCAGTCTTAGGGCTAGTACATCGCAACAAAAT
GAGACCATCGCGTCCCAGAATGCAGCAGCTAGCCAAACCCAAGCCGAAATCGGCAACCTCATCAGTCAAACAGAGGCTAA
AATTCGCGATTACCAGACAGCTAAGTCAGCTATTGAAACAGGTGCTTCCTTGGCCGGTCAGAATCTAGCCTACTCTCTTT
ACCAGTCCTACAAGTCTCAGGGCGAGGAAAATCCCCAAACTAAGGTTCAGGCAGTTGCACAGGTTGAAGCACAGATTTCT
CAGTTAGAATCTAGTCTTGCTACTTACCGTGTCCAGTATGCAGGTTCAGGTACCCAGCAAGCCTATGCGTCAGGGTTAAG
CAGTCAATTGGAATCCCTTAAATCCCAACACTTGGCAAAGGTTGGTCAGGAATTGACCCTTCTAGCCCAGAAAATTTTGG
AGGCAGAGTCAGGTAAGAAGGTACAGGGAAATCTTTTAGACAAGGGGAAAGTTACGGCGAGTGAGGATGGGGTGCTTCAT
CTTAATCCTGAGACCAGTGATTCTAGCATGGTTGCAGAAGGTGCCCTACTAGCCCAACTTTATCCATCTTTGGAAAGAGA
AGGGAAAGCCAAACTCACAGCTTATCTAAGTTCAAAATATGTAGCAAGAATCAAGGTCGGTGATTCTGTTCGCTATACTA
CGACTCATGATGCCGGGAATCAACTTTTCCTAGATTCTACTATTACAAGTATTGATGCGACAGCTACTAAGACTGAGAAA
GGGAATTTCTTTAAAATCGAGGCGGAGACTAATCTAACTTCGGAGCAGGCTGAAAAACTTAGGTACGGGGTGGAAGGCCG
CTTGCAGATGATTACGGGCAAGAAAAGTTACCTACGTTATTATTTGGATCAATTTTTGAACAAAGAGTAA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB Streptococcus pneumoniae TIGR4

100

100

1
  comB Streptococcus pneumoniae Rx1

98.886

100

0.989
  comB Streptococcus pneumoniae D39

98.886

100

0.989
  comB Streptococcus pneumoniae R6

98.886

100

0.989
  comB Streptococcus mitis SK321

94.655

100

0.947
  comB Streptococcus mitis NCTC 12261

94.209

100

0.942
  comB Streptococcus gordonii str. Challis substr. CH1

55.111

100

0.552

Multiple sequence alignment