Detailed information NTG0338415

Bioinformatically predicted

Overview

• Name: comGE/cglE
• Type: Machinery gene
• Locus tag: EQH19_RS09645
• Genome accession: NZ_CP035261
• Coordinates: 1878945..1879247 (-)
• Length: 100 a.a.
• NCBI ID: WP_000413382.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901924
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1873945..1884247

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH19_RS09615 (EQH19_10155)	rnpA	1874624..1874995 (-)	372	WP_000739246.1	ribonuclease P protein component	-
EQH19_RS10795	-	1875012..1875143 (-)	132	WP_000768904.1	hypothetical protein	-
EQH19_RS09620 (EQH19_10160)	-	1875144..1876334 (-)	1191	WP_000167757.1	acetate kinase	-
EQH19_RS09625 (EQH19_10165)	comYH	1876385..1877338 (-)	954	WP_000345135.1	class I SAM-dependent methyltransferase	Machinery gene
EQH19_RS09630 (EQH19_10170)	-	1877399..1877993 (-)	595	Protein_1891	class I SAM-dependent methyltransferase	-
EQH19_RS09635 (EQH19_10175)	comGG/cglG	1878130..1878543 (-)	414	WP_000265622.1	competence type IV pilus minor pilin ComGG	Machinery gene
EQH19_RS09640 (EQH19_10180)	comGF/cglF	1878521..1878982 (-)	462	WP_000250532.1	competence type IV pilus minor pilin ComGF	Machinery gene
EQH19_RS09645 (EQH19_10185)	comGE/cglE	1878945..1879247 (-)	303	WP_000413382.1	competence type IV pilus minor pilin ComGE	Machinery gene
EQH19_RS09650 (EQH19_10190)	comGD/cglD	1879210..1879614 (-)	405	WP_000588029.1	competence type IV pilus minor pilin ComGD	Machinery gene
EQH19_RS09655 (EQH19_10195)	comGC/cglC	1879607..1879933 (-)	327	WP_000738625.1	competence type IV pilus major pilin ComGC	Machinery gene
EQH19_RS09660 (EQH19_10200)	comGB/cglB	1879935..1880951 (-)	1017	WP_074017570.1	competence type IV pilus assembly protein ComGB	Machinery gene
EQH19_RS09665 (EQH19_10205)	comGA/cglA/cilD	1880899..1881840 (-)	942	WP_000249555.1	competence type IV pilus ATPase ComGA	Machinery gene
EQH19_RS09670 (EQH19_10210)	-	1881915..1882280 (-)	366	WP_000286415.1	DUF1033 family protein	-
EQH19_RS09675 (EQH19_10215)	-	1882431..1883489 (-)	1059	WP_000649471.1	zinc-dependent alcohol dehydrogenase family protein	-

Sequence

Protein

• Length: 100 a.a.
• Molecular weight: 11108.08 Da
• Isoelectric Point: 9.7273

>NTDB_id=338415 EQH19_RS09645 WP_000413382.1 1878945..1879247(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901924]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide

• Length: 303 bp

>NTDB_id=338415 EQH19_RS09645 WP_000413382.1 1878945..1879247(-) (comGE/cglE) [Streptococcus pneumoniae strain TVO_1901924]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCCTGCAGACGGGGCAAAATCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

• Type II secretory pathway pseudopilin (ComGE) (16-97)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGE/cglE	Streptococcus pneumoniae Rx1	100	100	1
comGE/cglE	Streptococcus pneumoniae D39	100	100	1
comGE/cglE	Streptococcus pneumoniae R6	100	100	1
comGE/cglE	Streptococcus pneumoniae TIGR4	100	100	1
comGE/cglE	Streptococcus mitis NCTC 12261	98	100	0.98
comGE/cglE	Streptococcus mitis SK321	98	100	0.98
comYE	Streptococcus mutans UA140	44.444	90	0.4
comYE	Streptococcus mutans UA159	44.444	90	0.4