Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   EQH19_RS09625 Genome accession   NZ_CP035261
Coordinates   1876385..1877338 (-) Length   317 a.a.
NCBI ID   WP_000345135.1    Uniprot ID   A0A2U3RW99
Organism   Streptococcus pneumoniae strain TVO_1901924     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1871385..1882338
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH19_RS09600 (EQH19_10140) - 1872146..1872769 (-) 624 WP_000932659.1 hypothetical protein -
  EQH19_RS09605 (EQH19_10145) jag 1872820..1873806 (-) 987 WP_000260025.1 RNA-binding cell elongation regulator Jag/EloR -
  EQH19_RS09610 (EQH19_10150) - 1873825..1874649 (-) 825 WP_000727904.1 membrane protein insertase YidC -
  EQH19_RS09615 (EQH19_10155) rnpA 1874624..1874995 (-) 372 WP_000739246.1 ribonuclease P protein component -
  EQH19_RS10795 - 1875012..1875143 (-) 132 WP_000768904.1 hypothetical protein -
  EQH19_RS09620 (EQH19_10160) - 1875144..1876334 (-) 1191 WP_000167757.1 acetate kinase -
  EQH19_RS09625 (EQH19_10165) comYH 1876385..1877338 (-) 954 WP_000345135.1 class I SAM-dependent methyltransferase Machinery gene
  EQH19_RS09630 (EQH19_10170) - 1877399..1877993 (-) 595 Protein_1891 class I SAM-dependent methyltransferase -
  EQH19_RS09635 (EQH19_10175) comGG/cglG 1878130..1878543 (-) 414 WP_000265622.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH19_RS09640 (EQH19_10180) comGF/cglF 1878521..1878982 (-) 462 WP_000250532.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH19_RS09645 (EQH19_10185) comGE/cglE 1878945..1879247 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH19_RS09650 (EQH19_10190) comGD/cglD 1879210..1879614 (-) 405 WP_000588029.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH19_RS09655 (EQH19_10195) comGC/cglC 1879607..1879933 (-) 327 WP_000738625.1 competence type IV pilus major pilin ComGC Machinery gene
  EQH19_RS09660 (EQH19_10200) comGB/cglB 1879935..1880951 (-) 1017 WP_074017570.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH19_RS09665 (EQH19_10205) comGA/cglA/cilD 1880899..1881840 (-) 942 WP_000249555.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH19_RS09670 (EQH19_10210) - 1881915..1882280 (-) 366 WP_000286415.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35756.99 Da        Isoelectric Point: 4.2748

>NTDB_id=338412 EQH19_RS09625 WP_000345135.1 1876385..1877338(-) (comYH) [Streptococcus pneumoniae strain TVO_1901924]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKENNQTLKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGAIFLTSLTKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVASRHQVASSQEHTYAHHLLMEQGLKYLKSDGYAIFLAPSDLLTSPQ
SDLLKEWLKEEASLVAMISLPENLFANAKQSKTIFILQKKNEIAVEPFVYPLASLQDASVLMKFKENFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=338412 EQH19_RS09625 WP_000345135.1 1876385..1877338(-) (comYH) [Streptococcus pneumoniae strain TVO_1901924]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAATAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAGGAGAACAATC
AAACCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTATTTTCTTGACCTCGCTTACTAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTGCTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGCCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTCGCGCCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGCTTAAGTACCTCAAGTCAGACGGATACGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTAAAAGAATGGCTGAAAGAAGAGGCGAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCCAAACAATCTAAGACTATTTTTATCTTACAGAAGAAAAATGAAATAGCAGTAGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAGAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2U3RW99

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.633

98.738

0.539
  comYH Streptococcus mutans UA159

54.313

98.738

0.536

Multiple sequence alignment