Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH20_RS02325 Genome accession   NZ_CP035260
Coordinates   472631..474307 (-) Length   558 a.a.
NCBI ID   WP_307774231.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901925     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 467631..479307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH20_RS02295 (EQH20_02440) - 467963..468292 (-) 330 WP_000132572.1 hypothetical protein -
  EQH20_RS02300 (EQH20_02445) - 468568..468906 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  EQH20_RS02305 (EQH20_02450) comE/blpR 468911..469648 (+) 738 WP_061476395.1 response regulator transcription factor Regulator
  EQH20_RS02310 (EQH20_02455) - 469662..471002 (+) 1341 WP_061647476.1 sensor histidine kinase -
  EQH20_RS02315 (EQH20_02460) blpC 471047..471202 (-) 156 WP_000358810.1 quorum-sensing system pheromone BlpC -
  EQH20_RS02320 (EQH20_02465) - 471259..472620 (-) 1362 WP_054369799.1 bacteriocin secretion accessory protein -
  EQH20_RS02325 (EQH20_02470) comA/nlmT 472631..474307 (-) 1677 WP_307774231.1 peptide cleavage/export ABC transporter Regulator
  EQH20_RS10255 comA/nlmT 474201..474788 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH20_RS02330 (EQH20_02475) blpI 475078..475275 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  EQH20_RS02335 (EQH20_02485) blpJ 475742..476011 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  EQH20_RS02340 (EQH20_02490) blpU 476080..476310 (+) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  EQH20_RS02345 (EQH20_02495) - 476313..476432 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  EQH20_RS02350 (EQH20_02500) - 476729..476890 (+) 162 WP_000727119.1 hypothetical protein -
  EQH20_RS02355 (EQH20_02505) - 476913..477271 (+) 359 Protein_468 immunity protein -
  EQH20_RS02360 (EQH20_02515) - 477900..478283 (+) 384 WP_000877381.1 hypothetical protein -
  EQH20_RS02365 (EQH20_02520) - 478335..479024 (+) 690 WP_000760514.1 CPBP family intramembrane glutamic endopeptidase -
  EQH20_RS02370 (EQH20_02525) blpZ 479066..479299 (+) 234 WP_000276498.1 immunity protein BlpZ -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62990.34 Da        Isoelectric Point: 7.1280

>NTDB_id=338292 EQH20_RS02325 WP_307774231.1 472631..474307(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901925]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDVLASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFKPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKAYELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=338292 EQH20_RS02325 WP_307774231.1 472631..474307(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901925]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGTCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTAAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAAAGCTTATGAATTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.531

99.821

0.724
  comA Streptococcus pneumoniae Rx1

67.204

100

0.672
  comA Streptococcus pneumoniae D39

67.204

100

0.672
  comA Streptococcus pneumoniae R6

67.204

100

0.672
  comA Streptococcus mitis NCTC 12261

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

66.846

100

0.668
  comA Streptococcus mitis SK321

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.547

100

0.667

Multiple sequence alignment