Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   EQH20_RS02305 Genome accession   NZ_CP035260
Coordinates   468911..469648 (+) Length   245 a.a.
NCBI ID   WP_061476395.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901925     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 463911..474648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH20_RS02275 (EQH20_02415) - 465243..465530 (-) 288 WP_000777760.1 hypothetical protein -
  EQH20_RS02280 (EQH20_02420) - 465540..465950 (-) 411 WP_001278301.1 HIT family protein -
  EQH20_RS02285 (EQH20_02425) pptA 466018..466749 (+) 732 WP_000889923.1 ABC transporter ATP-binding protein Regulator
  EQH20_RS02290 (EQH20_02430) - 466746..467795 (+) 1050 WP_061476401.1 ABC transporter permease -
  EQH20_RS02295 (EQH20_02440) - 467963..468292 (-) 330 WP_000132572.1 hypothetical protein -
  EQH20_RS02300 (EQH20_02445) - 468568..468906 (+) 339 WP_000682121.1 LytTR family DNA-binding domain-containing protein -
  EQH20_RS02305 (EQH20_02450) comE/blpR 468911..469648 (+) 738 WP_061476395.1 response regulator transcription factor Regulator
  EQH20_RS02310 (EQH20_02455) - 469662..471002 (+) 1341 WP_061647476.1 sensor histidine kinase -
  EQH20_RS02315 (EQH20_02460) blpC 471047..471202 (-) 156 WP_000358810.1 quorum-sensing system pheromone BlpC -
  EQH20_RS02320 (EQH20_02465) - 471259..472620 (-) 1362 WP_054369799.1 bacteriocin secretion accessory protein -
  EQH20_RS02325 (EQH20_02470) comA/nlmT 472631..474307 (-) 1677 WP_307774231.1 peptide cleavage/export ABC transporter Regulator

Sequence

Protein


Download         Length: 245 a.a.        Molecular weight: 28736.92 Da        Isoelectric Point: 6.4140

>NTDB_id=338291 EQH20_RS02305 WP_061476395.1 468911..469648(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901925]
MRIFVLEDDFSQQTRIETTIEKLLKAHHIIPSSFEVFGKPDQLLAEVHEKGAHQLFFLDIEIRNEEMKGLEVARKIRDRD
PYALIVFVTTHSEFMPLSFRYQVSALDYIDKALSAEEFESRIETALLYANSQDSKSLAEDCFYFKSKFAQFQYPFKEVYY
LETSTRPHRVILYTKTDRLEFTASLEEVLKQEPRLLQCHRSFLINPANVVHLDKKEKLLFFPNGGSCLIARYKVREVSEA
INNLH

Nucleotide


Download         Length: 738 bp        

>NTDB_id=338291 EQH20_RS02305 WP_061476395.1 468911..469648(+) (comE/blpR) [Streptococcus pneumoniae strain TVO_1901925]
ATGAGAATATTTGTTTTAGAAGATGATTTTTCCCAACAGACTAGAATTGAAACGACGATTGAGAAACTTTTGAAAGCACA
TCATATCATTCCTAGCTCTTTTGAGGTATTTGGCAAGCCGGACCAACTGCTGGCAGAGGTGCATGAGAAGGGGGCCCATC
AGCTATTCTTTTTGGACATTGAGATTCGAAATGAGGAGATGAAGGGGCTGGAAGTGGCTAGAAAGATTCGGGATCGGGAC
CCTTATGCCCTAATCGTCTTTGTGACGACTCACTCGGAGTTTATGCCTCTGTCCTTTCGCTACCAAGTGTCAGCTTTGGA
CTACATTGATAAGGCCCTTTCGGCAGAGGAGTTTGAATCTCGTATCGAGACAGCCCTCCTCTATGCCAATAGTCAAGATA
GTAAAAGTCTGGCGGAAGATTGCTTTTACTTTAAATCAAAATTTGCCCAATTCCAATATCCTTTTAAAGAGGTTTACTAT
CTCGAAACGTCCACAAGACCCCATCGTGTTATTCTCTATACCAAGACAGACAGGCTGGAATTTACAGCGAGTCTAGAGGA
GGTTCTCAAGCAGGAGCCTCGTCTCTTGCAGTGCCATCGCTCTTTTCTCATCAATCCTGCCAATGTGGTGCATTTAGATA
AGAAAGAAAAACTGCTTTTCTTTCCCAATGGTGGAAGTTGTCTAATCGCGCGTTATAAGGTCAGGGAAGTGTCTGAGGCT
ATTAATAACTTACACTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-241)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

53.909

99.184

0.535
  comE/comE1 Streptococcus equinus JB1

43.038

96.735

0.416
  comE/comE2 Streptococcus equinus JB1

38.43

98.776

0.38

Multiple sequence alignment