Detailed information NTG0338278

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: EQH21_RS10710
• Genome accession: NZ_CP035259
• Coordinates: 483095..483682 (-)
• Length: 195 a.a.
• NCBI ID: WP_001810858.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901926
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 478095..488682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH21_RS02460 (EQH21_02595)	-	478557..479897 (+)	1341	WP_001028653.1	sensor histidine kinase	-
EQH21_RS02465 (EQH21_02600)	blpC	479942..480097 (-)	156	WP_000358810.1	quorum-sensing system pheromone BlpC	-
EQH21_RS02470 (EQH21_02605)	-	480154..481515 (-)	1362	WP_001069085.1	bacteriocin secretion accessory protein	-
EQH21_RS10700	comA/nlmT	481526..482437 (-)	912	WP_001828567.1	ATP-binding cassette domain-containing protein	Regulator
EQH21_RS10705	blpA	482426..483150 (-)	725	Protein_495	peptide cleavage/export ABC transporter BlpA	-
EQH21_RS10710 (EQH21_02615)	comA/nlmT	483095..483682 (-)	588	WP_001810858.1	cysteine peptidase family C39 domain-containing protein	Regulator
EQH21_RS02480 (EQH21_02620)	blpI	483964..484161 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
EQH21_RS02485 (EQH21_02630)	blpJ	484628..484897 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
EQH21_RS02490 (EQH21_02635)	blpU	484966..485196 (+)	231	WP_000379964.1	bacteriocin-like peptide BlpU	-
EQH21_RS02495 (EQH21_02640)	-	485199..485318 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
EQH21_RS02500 (EQH21_02650)	-	485838..486156 (+)	319	Protein_501	immunity protein	-
EQH21_RS02505 (EQH21_02655)	-	486239..486622 (+)	384	WP_000877381.1	hypothetical protein	-
EQH21_RS02510 (EQH21_02660)	-	486674..487363 (+)	690	WP_000760515.1	CPBP family intramembrane glutamic endopeptidase	-
EQH21_RS02515 (EQH21_02665)	blpZ	487405..487653 (+)	249	WP_000276499.1	immunity protein BlpZ	-
EQH21_RS02520 (EQH21_02670)	-	487683..488294 (+)	612	WP_000394031.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22194.61 Da
• Isoelectric Point: 9.6497

>NTDB_id=338278 EQH21_RS10710 WP_001810858.1 483095..483682(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901926]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=338278 EQH21_RS10710 WP_001810858.1 483095..483682(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901926]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	60.44	93.333	0.564
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497