Detailed information NTG0338202

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: EQH22_RS10980
• Genome accession: NZ_CP035258
• Coordinates: 488316..488903 (-)
• Length: 195 a.a.
• NCBI ID: WP_001810858.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901927
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 483316..493903

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH22_RS02460 (EQH22_02620)	-	483780..485118 (+)	1339	Protein_492	sensor histidine kinase	-
EQH22_RS02465 (EQH22_02625)	blpC	485163..485318 (-)	156	WP_000358810.1	quorum-sensing system pheromone BlpC	-
EQH22_RS02470 (EQH22_02630)	-	485375..486736 (-)	1362	WP_001069085.1	bacteriocin secretion accessory protein	-
EQH22_RS10970	comA/nlmT	486747..487658 (-)	912	WP_001828567.1	ATP-binding cassette domain-containing protein	Regulator
EQH22_RS10975	blpA	487647..488371 (-)	725	Protein_496	peptide cleavage/export ABC transporter BlpA	-
EQH22_RS10980 (EQH22_02640)	comA/nlmT	488316..488903 (-)	588	WP_001810858.1	cysteine peptidase family C39 domain-containing protein	Regulator
EQH22_RS02480 (EQH22_02645)	blpI	489185..489382 (+)	198	WP_001093259.1	bacteriocin-like peptide BlpI	-
EQH22_RS02485 (EQH22_02655)	blpJ	489849..490118 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
EQH22_RS02490 (EQH22_02660)	blpU	490187..490417 (+)	231	WP_000379964.1	bacteriocin-like peptide BlpU	-
EQH22_RS02495 (EQH22_02665)	-	490420..490539 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
EQH22_RS02500 (EQH22_02675)	-	491059..491377 (+)	319	Protein_502	immunity protein	-
EQH22_RS02505 (EQH22_02680)	-	491460..491843 (+)	384	WP_000877381.1	hypothetical protein	-
EQH22_RS02510 (EQH22_02685)	-	491895..492584 (+)	690	WP_000760515.1	CPBP family intramembrane glutamic endopeptidase	-
EQH22_RS02515 (EQH22_02690)	blpZ	492626..492874 (+)	249	WP_000276499.1	immunity protein BlpZ	-
EQH22_RS02520 (EQH22_02695)	-	492904..493515 (+)	612	WP_000394031.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22194.61 Da
• Isoelectric Point: 9.6497

>NTDB_id=338202 EQH22_RS10980 WP_001810858.1 488316..488903(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901927]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFSEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=338202 EQH22_RS10980 WP_001810858.1 488316..488903(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901927]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTCTGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	60.44	93.333	0.564
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497