Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH24_RS11705 Genome accession   NZ_CP035256
Coordinates   540347..540934 (-) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 535347..545934
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS02770 (EQH24_02930) - 535811..537151 (+) 1341 WP_001028044.1 sensor histidine kinase -
  EQH24_RS02775 (EQH24_02935) blpC 537193..537348 (-) 156 WP_000358817.1 quorum-sensing system pheromone BlpC -
  EQH24_RS02780 (EQH24_02940) - 537405..538766 (-) 1362 Protein_555 bacteriocin secretion accessory protein -
  EQH24_RS02785 (EQH24_02945) comA/nlmT 538777..540453 (-) 1677 WP_196299874.1 peptide cleavage/export ABC transporter Regulator
  EQH24_RS11705 comA/nlmT 540347..540934 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH24_RS02790 (EQH24_02955) blpI 541208..541405 (+) 198 WP_001093261.1 bacteriocin-like peptide BlpI -
  EQH24_RS02795 (EQH24_02965) blpJ 541872..542141 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  EQH24_RS02800 (EQH24_02970) blpU 542210..542440 (+) 231 WP_000379967.1 bacteriocin-like peptide BlpU -
  EQH24_RS02805 (EQH24_02975) - 542443..542562 (+) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  EQH24_RS02810 (EQH24_02980) - 542859..543023 (+) 165 WP_000727118.1 hypothetical protein -
  EQH24_RS02815 (EQH24_02985) - 543020..543424 (+) 405 WP_000846944.1 hypothetical protein -
  EQH24_RS02820 (EQH24_02990) - 543627..544432 (+) 806 Protein_564 IS5 family transposase -
  EQH24_RS02825 (EQH24_02995) blpM 544582..544836 (+) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  EQH24_RS02830 (EQH24_03000) blpN 544852..545055 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  EQH24_RS02835 (EQH24_03010) cipB 545299..545448 (+) 150 WP_001820573.1 bacteriocin-like peptide BlpO Regulator
  EQH24_RS02840 (EQH24_03015) - 545552..545671 (+) 120 WP_000346296.1 PncF family bacteriocin immunity protein -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=338046 EQH24_RS11705 WP_000205166.1 540347..540934(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901930]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=338046 EQH24_RS11705 WP_000205166.1 540347..540934(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901930]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497

Multiple sequence alignment