Detailed information NTG0337977

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: EQH24_RS02785
• Genome accession: NZ_CP035256
• Coordinates: 538777..540453 (-)
• Length: 558 a.a.
• NCBI ID: WP_196299874.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901930
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 533777..545453

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH24_RS02755 (EQH24_02915)	-	534112..534441 (-)	330	WP_000132572.1	hypothetical protein	-
EQH24_RS02760 (EQH24_02920)	-	534717..535055 (+)	339	WP_000876676.1	LytTR family DNA-binding domain-containing protein	-
EQH24_RS02765 (EQH24_02925)	comE/blpR	535060..535797 (+)	738	WP_023396586.1	response regulator transcription factor	Regulator
EQH24_RS02770 (EQH24_02930)	-	535811..537151 (+)	1341	WP_001028044.1	sensor histidine kinase	-
EQH24_RS02775 (EQH24_02935)	blpC	537193..537348 (-)	156	WP_000358817.1	quorum-sensing system pheromone BlpC	-
EQH24_RS02780 (EQH24_02940)	-	537405..538766 (-)	1362	Protein_555	bacteriocin secretion accessory protein	-
EQH24_RS02785 (EQH24_02945)	comA/nlmT	538777..540453 (-)	1677	WP_196299874.1	peptide cleavage/export ABC transporter	Regulator
EQH24_RS11705	comA/nlmT	540347..540934 (-)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
EQH24_RS02790 (EQH24_02955)	blpI	541208..541405 (+)	198	WP_001093261.1	bacteriocin-like peptide BlpI	-
EQH24_RS02795 (EQH24_02965)	blpJ	541872..542141 (+)	270	WP_001093248.1	bacteriocin-like peptide BlpJ	-
EQH24_RS02800 (EQH24_02970)	blpU	542210..542440 (+)	231	WP_000379967.1	bacteriocin-like peptide BlpU	-
EQH24_RS02805 (EQH24_02975)	-	542443..542562 (+)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
EQH24_RS02810 (EQH24_02980)	-	542859..543023 (+)	165	WP_000727118.1	hypothetical protein	-
EQH24_RS02815 (EQH24_02985)	-	543020..543424 (+)	405	WP_000846944.1	hypothetical protein	-
EQH24_RS02820 (EQH24_02990)	-	543627..544432 (+)	806	Protein_564	IS5 family transposase	-
EQH24_RS02825 (EQH24_02995)	blpM	544582..544836 (+)	255	WP_000379877.1	two-peptide bacteriocin subunit BlpM	-
EQH24_RS02830 (EQH24_03000)	blpN	544852..545055 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
EQH24_RS02835 (EQH24_03010)	cipB	545299..545448 (+)	150	WP_001820573.1	bacteriocin-like peptide BlpO	Regulator

Sequence

Protein

• Length: 558 a.a.
• Molecular weight: 62923.20 Da
• Isoelectric Point: 6.7844

>NTDB_id=337977 EQH24_RS02785 WP_196299874.1 538777..540453(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901930]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKS
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide

• Length: 1677 bp

>NTDB_id=337977 EQH24_RS02785 WP_196299874.1 538777..540453(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901930]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGAGTCTTGCTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGATCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAATCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGCCACCAAGAGTTAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (341-490)

• ABC transporter transmembrane region (ABC_membrane) (10-279)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	72.89	99.821	0.728
comA	Streptococcus mitis NCTC 12261	67.204	100	0.672
comA	Streptococcus pneumoniae D39	66.846	100	0.668
comA	Streptococcus pneumoniae R6	66.846	100	0.668
comA	Streptococcus pneumoniae Rx1	66.846	100	0.668
comA	Streptococcus mitis SK321	66.667	100	0.667
comA	Streptococcus gordonii str. Challis substr. CH1	66.547	100	0.667
comA	Streptococcus pneumoniae TIGR4	66.487	100	0.665