Detailed information NTG0338039

Bioinformatically predicted

Overview

• Name: comFC/cflB
• Type: Machinery gene
• Locus tag: EQH24_RS11385
• Genome accession: NZ_CP035256
• Coordinates: 2190207..2190869 (-)
• Length: 220 a.a.
• NCBI ID: WP_023396533.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901930
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2185207..2195869

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH24_RS11360 (EQH24_11925)	-	2185358..2185624 (-)	267	WP_001278167.1	Veg family protein	-
EQH24_RS11365 (EQH24_11930)	dnaB	2185626..2186978 (-)	1353	WP_000852486.1	replicative DNA helicase	-
EQH24_RS11370 (EQH24_11935)	rplI	2187022..2187474 (-)	453	WP_000864220.1	50S ribosomal protein L9	-
EQH24_RS11375 (EQH24_11940)	-	2187471..2189444 (-)	1974	WP_023396532.1	DHH family phosphoesterase	-
EQH24_RS11380 (EQH24_11945)	hpf	2189579..2190127 (-)	549	WP_000599104.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
EQH24_RS11385 (EQH24_11950)	comFC/cflB	2190207..2190869 (-)	663	WP_023396533.1	ComF family protein	Machinery gene
EQH24_RS11390 (EQH24_11955)	comFA/cflA	2190866..2192164 (-)	1299	WP_023396534.1	DEAD/DEAH box helicase	Machinery gene
EQH24_RS11395 (EQH24_11960)	-	2192220..2192855 (+)	636	WP_023396535.1	YigZ family protein	-
EQH24_RS11400 (EQH24_11965)	cysK	2193140..2194060 (+)	921	WP_000029866.1	cysteine synthase A	-
EQH24_RS11405 (EQH24_11975)	-	2194135..2194673 (-)	539	Protein_2242	transposase	-
EQH24_RS11410 (EQH24_11980)	-	2194646..2194933 (+)	288	Protein_2243	transposase	-
EQH24_RS11415 (EQH24_11985)	tnpB	2195088..2195411 (-)	324	WP_000586647.1	IS66 family insertion sequence element accessory protein TnpB	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 25255.12 Da
• Isoelectric Point: 7.3688

>NTDB_id=338039 EQH24_RS11385 WP_023396533.1 2190207..2190869(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901930]
MKCLLCGQTMKTVLTFSSLLLLRNDDSCLCSDCDSTFERIGEENCPNCMKTELSTKCQDCQLWCKEGIEVSHRAIFTYNQ
AMKDFFSRYKFDGDFLLRKVFASFLSEELKKYKEYQFVVIPLSPDRYANRGFNQVEGLVEAAGFEYLDLLEKREERASSS
KNRSERLGTELPFFIKSGVTIPKKILLIDDIYTTGATINRVKKLLEEAGAKDVKTFSLVR

Nucleotide

• Length: 663 bp

>NTDB_id=338039 EQH24_RS11385 WP_023396533.1 2190207..2190869(-) (comFC/cflB) [Streptococcus pneumoniae strain TVO_1901930]
ATGAAGTGCTTGTTATGTGGGCAGACTATGAAGACTGTTTTAACTTTTAGTAGTCTCTTACTTCTGAGGAATGATGACTC
TTGTCTTTGTTCAGACTGTGATTCTACTTTTGAAAGAATTGGGGAAGAGAACTGTCCAAATTGTATGAAAACAGAGTTGT
CAACAAAGTGTCAAGATTGTCAACTTTGGTGTAAAGAAGGAATTGAAGTCAGTCATAGAGCGATTTTTACTTACAATCAA
GCTATGAAGGATTTTTTCAGTCGGTATAAGTTTGATGGAGACTTCCTGTTAAGAAAAGTTTTCGCTTCATTTTTAAGTGA
GGAGTTGAAAAAGTACAAAGAGTATCAATTTGTTGTAATTCCCCTAAGTCCTGATAGATATGCTAATAGAGGATTTAATC
AGGTTGAGGGCTTGGTAGAGGCAGCAGGCTTTGAGTATCTGGATTTATTAGAGAAAAGAGAAGAGAGAGCCAGTTCTTCT
AAAAATCGTTCAGAGCGCTTGGGGACAGAACTTCCTTTCTTTATTAAAAGTGGAGTCACTATTCCTAAAAAAATCCTACT
TATAGATGATATCTATACTACAGGAGCAACTATAAATCGTGTTAAGAAACTGTTGGAAGAAGCTGGTGCTAAGGATGTAA
AAACATTTTCCCTTGTAAGATGA

Domains

Predicted by InterproScan.

• Phosphoribosyl transferase domain (Pribosyltran) (153-219)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comFC/cflB	Streptococcus pneumoniae TIGR4	99.545	100	0.995
comFC/cflB	Streptococcus pneumoniae Rx1	99.091	100	0.991
comFC/cflB	Streptococcus pneumoniae D39	99.091	100	0.991
comFC/cflB	Streptococcus pneumoniae R6	99.091	100	0.991
comFC/cflB	Streptococcus mitis NCTC 12261	91.364	100	0.914
comFC/cflB	Streptococcus mitis SK321	90.909	100	0.909
comFC	Bacillus subtilis subsp. subtilis str. 168	35.088	100	0.364