Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   EQH24_RS11390 Genome accession   NZ_CP035256
Coordinates   2190866..2192164 (-) Length   432 a.a.
NCBI ID   WP_023396534.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901930     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2185866..2197164
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH24_RS11370 (EQH24_11935) rplI 2187022..2187474 (-) 453 WP_000864220.1 50S ribosomal protein L9 -
  EQH24_RS11375 (EQH24_11940) - 2187471..2189444 (-) 1974 WP_023396532.1 DHH family phosphoesterase -
  EQH24_RS11380 (EQH24_11945) hpf 2189579..2190127 (-) 549 WP_000599104.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  EQH24_RS11385 (EQH24_11950) comFC/cflB 2190207..2190869 (-) 663 WP_023396533.1 ComF family protein Machinery gene
  EQH24_RS11390 (EQH24_11955) comFA/cflA 2190866..2192164 (-) 1299 WP_023396534.1 DEAD/DEAH box helicase Machinery gene
  EQH24_RS11395 (EQH24_11960) - 2192220..2192855 (+) 636 WP_023396535.1 YigZ family protein -
  EQH24_RS11400 (EQH24_11965) cysK 2193140..2194060 (+) 921 WP_000029866.1 cysteine synthase A -
  EQH24_RS11405 (EQH24_11975) - 2194135..2194673 (-) 539 Protein_2242 transposase -
  EQH24_RS11410 (EQH24_11980) - 2194646..2194933 (+) 288 Protein_2243 transposase -
  EQH24_RS11415 (EQH24_11985) tnpB 2195088..2195411 (-) 324 WP_000586647.1 IS66 family insertion sequence element accessory protein TnpB -
  EQH24_RS11420 (EQH24_11990) tsf 2195657..2196697 (-) 1041 WP_000808063.1 translation elongation factor Ts -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49543.51 Da        Isoelectric Point: 8.5173

>NTDB_id=338040 EQH24_RS11390 WP_023396534.1 2190866..2192164(-) (comFA/cflA) [Streptococcus pneumoniae strain TVO_1901930]
MKVNLDYLGRLFTENELTEEERQLAEKFPAMRKEKGKLFCQRCNSTILEEWYLPIGAYYCRECLLMKRVRSDQTLYYFPQ
EDFPKQDVLKWRGQLTPFQEKVSEGLLQAVDKQKPTLVHAVTGAGKTEMIYQVVAKVINAGGAVCLASPRIDVCLELYKR
LQQDFSCGIALLHGESEPYFRTPLVVATTHQLLKFYQAFDLLIVDEVDAFPYVDNPTLYHAVKNSVKENGLRIFLTATST
NELDKKVCLGELKRLSLPRRFHGNPLIIPKPIWLSDFNRYLDKNRLSPKLKSYIEKQRKTAYPLLIFASEIKKGEQLKEI
LQEQFPNEKIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGDLLFFHDGLNASIKKAIKEIQMMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=338040 EQH24_RS11390 WP_023396534.1 2190866..2192164(-) (comFA/cflA) [Streptococcus pneumoniae strain TVO_1901930]
ATGAAAGTAAATTTAGATTATCTCGGTCGTTTATTTACTGAGAATGAATTAACAGAAGAAGAACGTCAGTTGGCGGAGAA
ATTTCCAGCAATGAGAAAGGAGAAGGGGAAACTTTTCTGTCAACGTTGTAATAGTACTATTCTAGAAGAATGGTATTTGC
CCATCGGTGCTTACTATTGTCGAGAGTGCTTGCTGATGAAGCGAGTCAGAAGTGATCAAACTTTATACTATTTTCCGCAG
GAGGATTTTCCGAAGCAAGATGTTCTCAAATGGCGCGGCCAATTAACTCCTTTTCAAGAGAAGGTGTCAGAGGGACTGCT
TCAAGCAGTAGACAAGCAAAAACCAACCTTAGTTCATGCGGTAACAGGAGCTGGAAAGACAGAAATGATTTATCAAGTAG
TGGCTAAAGTGATCAATGCGGGTGGTGCAGTGTGTTTGGCTAGTCCTCGCATAGATGTTTGTTTGGAGCTGTACAAGCGC
CTGCAACAGGATTTTTCTTGCGGGATAGCTTTGCTACATGGAGAATCGGAACCTTATTTTCGAACACCACTAGTTGTTGC
AACAACCCATCAGTTATTGAAGTTTTATCAAGCTTTTGATTTGCTGATAGTGGATGAAGTAGATGCTTTTCCTTATGTTG
ATAATCCCACGCTTTACCATGCTGTCAAGAATAGTGTAAAGGAGAATGGATTGAGAATCTTTTTAACAGCGACTTCGACC
AATGAGTTAGATAAAAAGGTCTGTTTAGGAGAACTAAAAAGACTGAGTTTACCGAGACGGTTTCATGGAAATCCGTTGAT
TATTCCAAAACCAATTTGGTTATCGGATTTTAATCGCTACTTAGATAAGAATCGTTTGTCACCAAAGTTAAAGTCCTATA
TTGAGAAGCAGAGAAAGACAGCTTATCCGTTACTCATTTTTGCTTCAGAAATTAAGAAAGGGGAGCAGTTAAAAGAAATC
TTACAGGAGCAATTTCCAAATGAGAAAATTGGCTTTGTATCTTCTGTAACAGAGGATCGATTAGAGCAAGTACAAGCTTT
TCGAGATGGAGAACTGACAATACTTATCAGTACGACAATCTTGGAGCGTGGAGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAGGCCAATCATCGTTTGTTTACCAAGTCTAGTTTGATTCAGATTGGTGGACGAGTTGGACGAAGCATGGATAGA
CCGACAGGAGATTTGCTTTTCTTCCATGATGGGTTAAATGCTTCAATCAAGAAGGCGATTAAGGAAATTCAGATGATGAA
TAAGGAGGCTGGTCTATGA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(94-238)

Helicase conserved C-terminal domain (Helicase_C)

(293-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

98.843

100

0.988
  comFA/cflA Streptococcus pneumoniae D39

98.843

100

0.988
  comFA/cflA Streptococcus pneumoniae R6

98.843

100

0.988
  comFA/cflA Streptococcus pneumoniae TIGR4

98.611

100

0.986
  comFA/cflA Streptococcus mitis NCTC 12261

93.287

100

0.933
  comFA/cflA Streptococcus mitis SK321

92.13

100

0.921
  comFA Lactococcus lactis subsp. cremoris KW2

52.513

92.13

0.484
  comFA Latilactobacillus sakei subsp. sakei 23K

38.747

99.769

0.387

Multiple sequence alignment