Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH26_RS02735 Genome accession   NZ_CP035254
Coordinates   527214..528890 (-) Length   558 a.a.
NCBI ID   WP_307774213.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901932     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 522214..533890
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH26_RS02715 (EQH26_02890) - 522538..523878 (+) 1341 WP_000275285.1 sensor histidine kinase -
  EQH26_RS02720 (EQH26_02895) blpC 523922..524077 (-) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  EQH26_RS02725 (EQH26_02900) - 524276..525622 (+) 1347 WP_001821937.1 IS1380-like element ISSpn5 family transposase -
  EQH26_RS02730 (EQH26_02905) - 525842..527203 (-) 1362 WP_001069093.1 bacteriocin secretion accessory protein -
  EQH26_RS02735 (EQH26_02910) comA/nlmT 527214..528890 (-) 1677 WP_307774213.1 peptide cleavage/export ABC transporter Regulator
  EQH26_RS10920 comA/nlmT 528784..529371 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH26_RS02740 (EQH26_02915) blpI 529653..529850 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  EQH26_RS02745 (EQH26_02925) blpJ 530317..530586 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  EQH26_RS02750 (EQH26_02930) blpK 530655..530903 (+) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  EQH26_RS02755 (EQH26_02940) blpU 531147..531377 (+) 231 WP_001093267.1 bacteriocin-like peptide BlpU -
  EQH26_RS02760 (EQH26_02945) - 531380..531499 (+) 120 WP_001821949.1 PncF family bacteriocin immunity protein -
  EQH26_RS02765 (EQH26_02955) - 531980..532338 (+) 359 Protein_554 immunity protein -
  EQH26_RS02770 (EQH26_02965) - 532967..533350 (+) 384 WP_000877381.1 hypothetical protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62889.17 Da        Isoelectric Point: 6.7844

>NTDB_id=337898 EQH26_RS02735 WP_307774213.1 527214..528890(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901932]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILKACEVAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLISLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=337898 EQH26_RS02735 WP_307774213.1 527214..528890(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901932]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGAGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTTCTTTCTCTTATTTCTATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCAAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTTCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCACAACAAGCCTATATCTTTAATGGCTCTATTTTGGAAAACTTAACCTTGGGCGGTAATCATATGAT
TAGTCAAGAAGATATTCTAAAAGCTTGTGAAGTAGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAAAAGCAACGAATCGCTCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGATGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATATCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAAGCGCAAGGATTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

72.89

99.821

0.728
  comA Streptococcus pneumoniae Rx1

67.025

100

0.67
  comA Streptococcus pneumoniae D39

67.025

100

0.67
  comA Streptococcus pneumoniae R6

67.025

100

0.67
  comA Streptococcus mitis NCTC 12261

67.025

100

0.67
  comA Streptococcus pneumoniae TIGR4

66.667

100

0.667
  comA Streptococcus gordonii str. Challis substr. CH1

66.369

100

0.665
  comA Streptococcus mitis SK321

66.487

100

0.665

Multiple sequence alignment