Detailed information NTG0337829

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: EQH28_RS05730
• Genome accession: NZ_CP035252
• Coordinates: 1153782..1154630 (-)
• Length: 282 a.a.
• NCBI ID: WP_061818183.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901934
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 1148782..1159630

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH28_RS05715 (EQH28_06055)	-	1149134..1149493 (-)	360	WP_001237219.1	YbaN family protein	-
EQH28_RS05720 (EQH28_06060)	topA	1149599..1151686 (-)	2088	WP_000179650.1	type I DNA topoisomerase	-
EQH28_RS05725 (EQH28_06065)	-	1151854..1152897 (-)	1044	WP_001812957.1	TIGR00341 family protein	-
EQH28_RS05730 (EQH28_06070)	dprA/cilB/dalA	1153782..1154630 (-)	849	WP_061818183.1	DNA-processing protein DprA	Machinery gene
EQH28_RS05735 (EQH28_06075)	-	1154726..1155415 (-)	690	WP_000643971.1	sugar phosphate nucleotidyltransferase	-
EQH28_RS05740 (EQH28_06080)	-	1155427..1156305 (-)	879	WP_000837617.1	DMT family transporter	-
EQH28_RS05745 (EQH28_06085)	licA	1156295..1157164 (-)	870	WP_041172807.1	choline kinase LicA	-
EQH28_RS05750 (EQH28_06090)	-	1157181..1158203 (-)	1023	WP_000609886.1	ribitol-5-phosphate dehydrogenase	-
EQH28_RS05755 (EQH28_06095)	-	1158208..1158915 (-)	708	WP_000638508.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31122.76 Da
• Isoelectric Point: 5.4048

>NTDB_id=337829 EQH28_RS05730 WP_061818183.1 1153782..1154630(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901934]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGYRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLVLSEYGPGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=337829 EQH28_RS05730 WP_061818183.1 1153782..1154630(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain TVO_1901934]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATCTCAGGTTACCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTCTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAATAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGGTTCTAAGTGAATATGGACCTGGTGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACGTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.645	100	0.996
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.645	100	0.996
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	98.227	100	0.982
dprA/cilB/dalA	Streptococcus mitis SK321	97.518	100	0.975
dprA	Streptococcus mutans UA159	63.214	99.291	0.628
dprA	Lactococcus lactis subsp. cremoris KW2	55.714	99.291	0.553
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362