Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH31_RS02525 Genome accession   NZ_CP035249
Coordinates   496911..498401 (-) Length   496 a.a.
NCBI ID   WP_001818755.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901938     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 491911..503401
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH31_RS02495 (EQH31_02665) - 492243..492572 (-) 330 WP_000132572.1 hypothetical protein -
  EQH31_RS02500 (EQH31_02670) - 492849..493187 (+) 339 WP_000682133.1 LytTR family DNA-binding domain-containing protein -
  EQH31_RS02505 (EQH31_02675) comE/blpR 493192..493929 (+) 738 WP_001219141.1 response regulator transcription factor Regulator
  EQH31_RS02510 (EQH31_02680) - 493943..495283 (+) 1341 WP_001099892.1 sensor histidine kinase -
  EQH31_RS02515 (EQH31_02685) blpC 495327..495482 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  EQH31_RS02520 (EQH31_02690) - 495539..496900 (-) 1362 WP_001069071.1 bacteriocin secretion accessory protein -
  EQH31_RS02525 (EQH31_02695) comA/nlmT 496911..498401 (-) 1491 WP_001818755.1 peptide cleavage/export ABC transporter Regulator
  EQH31_RS11120 (EQH31_02700) comA/nlmT 498493..499080 (-) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH31_RS02530 (EQH31_02705) blpI 499362..499559 (+) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  EQH31_RS02535 (EQH31_02715) blpJ 500026..500295 (+) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  EQH31_RS02540 (EQH31_02720) blpU 500364..500594 (+) 231 WP_000379964.1 bacteriocin-like peptide BlpU -
  EQH31_RS02545 (EQH31_02725) - 500597..500716 (+) 120 WP_001844187.1 PncF family bacteriocin immunity protein -
  EQH31_RS02550 (EQH31_02730) - 501015..501179 (+) 165 WP_000727118.1 hypothetical protein -
  EQH31_RS02555 (EQH31_02735) - 501176..501571 (+) 396 WP_000846569.1 hypothetical protein -
  EQH31_RS02560 (EQH31_02740) - 501585..502399 (-) 815 Protein_512 IS5-like element IS1515 family transposase -

Sequence

Protein


Download         Length: 496 a.a.        Molecular weight: 56059.95 Da        Isoelectric Point: 6.6428

>NTDB_id=337657 EQH31_RS02525 WP_001818755.1 496911..498401(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901938]
MSFSRDYLLTVLSQRLSIDVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLL
AQNPNLFLLSLLSIPIYMFIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKS
FKLSKYSILQTSLKQGTKLVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLPSAKVANNRLNEV
YLVESEFQVQENPVHSHFLMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHI
SINHQDIKNIDKKVLRRHINYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGL
SGGQKQRIALARALLTKSPVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSH
QELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1491 bp        

>NTDB_id=337657 EQH31_RS02525 WP_001818755.1 496911..498401(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901938]
ATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATTGATGTGATTTTATCCTATATTCGCCA
TATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTA
TTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGGGGAGTCTTGCTG
GCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACC
TTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTG
AAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCC
TTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATG
GTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTA
CAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCCATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTC
TATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGA
CCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCC
TAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGGCATATT
TCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCCCAACAAGCCTA
TATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTT
GTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTA
TCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAATCTCCTGTTTTAATACTAGACGAAGCTAC
TAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCTAACTGATAAAACCATTCTCTTTGTAG
CCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCAC
CAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(279-428)

ABC transporter transmembrane region (ABC_membrane)

(2-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.333

99.798

0.732
  comA Streptococcus gordonii str. Challis substr. CH1

67.002

100

0.671
  comA Streptococcus mitis NCTC 12261

67.137

100

0.671
  comA Streptococcus pneumoniae Rx1

66.734

100

0.667
  comA Streptococcus pneumoniae D39

66.734

100

0.667
  comA Streptococcus pneumoniae R6

66.734

100

0.667
  comA Streptococcus mitis SK321

66.532

100

0.665
  comA Streptococcus pneumoniae TIGR4

66.532

100

0.665

Multiple sequence alignment