Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGB/cglB   Type   Machinery gene
Locus tag   EQH34_RS09335 Genome accession   NZ_CP035246
Coordinates   1837570..1838586 (-) Length   338 a.a.
NCBI ID   WP_076750272.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901941     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1832570..1843586
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH34_RS10445 - 1832647..1832778 (-) 132 WP_000768904.1 hypothetical protein -
  EQH34_RS09295 (EQH34_09845) - 1832779..1833969 (-) 1191 WP_000167766.1 acetate kinase -
  EQH34_RS09300 (EQH34_09850) comYH 1834020..1834973 (-) 954 WP_000345101.1 class I SAM-dependent methyltransferase Machinery gene
  EQH34_RS09305 (EQH34_09855) - 1835034..1835628 (-) 595 Protein_1827 class I SAM-dependent methyltransferase -
  EQH34_RS09310 (EQH34_09860) comGG/cglG 1835765..1836178 (-) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  EQH34_RS09315 (EQH34_09865) comGF/cglF 1836156..1836617 (-) 462 WP_000250542.1 competence type IV pilus minor pilin ComGF Machinery gene
  EQH34_RS09320 (EQH34_09870) comGE/cglE 1836580..1836882 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  EQH34_RS09325 (EQH34_09875) comGD/cglD 1836845..1837249 (-) 405 WP_000588013.1 competence type IV pilus minor pilin ComGD Machinery gene
  EQH34_RS09330 (EQH34_09880) comGC/cglC 1837242..1837568 (-) 327 WP_000738626.1 comG operon protein ComGC Machinery gene
  EQH34_RS09335 (EQH34_09885) comGB/cglB 1837570..1838586 (-) 1017 WP_076750272.1 competence type IV pilus assembly protein ComGB Machinery gene
  EQH34_RS09340 (EQH34_09890) comGA/cglA/cilD 1838534..1839475 (-) 942 WP_000249556.1 competence type IV pilus ATPase ComGA Machinery gene
  EQH34_RS09345 (EQH34_09895) - 1839551..1839916 (-) 366 WP_000286415.1 DUF1033 family protein -
  EQH34_RS09350 (EQH34_09900) - 1840067..1841125 (-) 1059 WP_000649466.1 zinc-dependent alcohol dehydrogenase family protein -
  EQH34_RS09355 (EQH34_09905) nagA 1841288..1842439 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -

Sequence

Protein


Download         Length: 338 a.a.        Molecular weight: 38609.67 Da        Isoelectric Point: 9.4800

>NTDB_id=337474 EQH34_RS09335 WP_076750272.1 1837570..1838586(-) (comGB/cglB) [Streptococcus pneumoniae strain TVO_1901941]
MDISQVFRLRRKKLATAKQKNIITLFNNLFSSGFHLVETISFLDRSALLDKQCVTQMRVGLSQGKSFSEMMESLGCSSAI
VTQLSLAEVHGNLHLSLGKIEEYLDNLAKVKKKLIEVATYPLILLDFLLLIMLGLRNYLLPQLDSSNIATQIIGNLPQIF
LGMIVFVSVGILLALTFYKRSSKMRVFSILARLPFIGIFVQTYLTAYYAREWGNMISQGMELTQIFQMMQEQGSQLFKEI
GQDLAQTLKNGREFSQTIGTYPFFRKELSLIIEYGEVKSKLGSELEIYAEKTWEAFFTRVNRTMNLVQPLVFIFVALIIV
LLYAAMLMPMYQNMEVNF

Nucleotide


Download         Length: 1017 bp        

>NTDB_id=337474 EQH34_RS09335 WP_076750272.1 1837570..1838586(-) (comGB/cglB) [Streptococcus pneumoniae strain TVO_1901941]
ATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAAGCAAAAAAATATCATCACCCTATTTAA
CAATCTCTTTTCTAGCGGTTTTCATCTGGTGGAGACTATCTCCTTTTTAGATAGGAGTGCTTTGTTGGACAAGCAGTGTG
TGACCCAGATGCGTGTGGGCTTGTCTCAGGGGAAATCATTCTCAGAAATGATGGAAAGTTTGGGATGTTCAAGTGCTATT
GTCACTCAGTTATCCCTAGCTGAAGTTCATGGCAATCTCCACCTGAGTTTGGGAAAGATAGAAGAATATCTGGACAATCT
GGCCAAGGTCAAGAAAAAATTGATTGAAGTAGCGACCTATCCCTTGATTTTGCTGGATTTTCTTCTCTTAATTATGCTGG
GGCTACGGAATTACCTGCTCCCACAACTGGATAGTAGCAATATTGCCACCCAAATTATCGGTAATCTGCCACAAATCTTT
CTAGGAATGATAGTTTTTGTTTCAGTAGGTATCCTTTTAGCACTCACTTTTTATAAAAGAAGTTCTAAGATGCGCGTCTT
TTCTATCTTAGCACGCCTTCCCTTTATTGGAATCTTTGTGCAGACCTATTTGACAGCCTATTATGCACGTGAATGGGGGA
ATATGATTTCACAGGGAATGGAGTTGACGCAGATTTTTCAAATGATGCAGGAACAAGGTTCCCAGCTCTTTAAAGAAATC
GGTCAAGATCTGGCTCAAACCCTGAAAAATGGCCGTGAATTTTCTCAGACGATAGGAACCTATCCTTTCTTTAGGAAGGA
ATTGAGTCTCATCATAGAGTATGGGGAAGTTAAGTCCAAGCTGGGTAGTGAGTTGGAAATCTATGCTGAAAAAACTTGGG
AAGCCTTTTTTACCCGAGTCAACCGCACCATGAATTTGGTGCAGCCACTGGTTTTTATCTTTGTGGCACTGATTATCGTT
TTACTTTATGCGGCAATGCTCATGCCTATGTATCAAAATATGGAGGTAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(24-141)

Type II secretion system (T2SS), protein F (T2SSF)

(209-329)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGB/cglB Streptococcus pneumoniae Rx1

97.633

100

0.976
  comGB/cglB Streptococcus pneumoniae D39

97.633

100

0.976
  comGB/cglB Streptococcus pneumoniae R6

97.633

100

0.976
  comGB/cglB Streptococcus pneumoniae TIGR4

97.633

100

0.976
  comGB/cglB Streptococcus mitis NCTC 12261

94.97

100

0.95
  comGB/cglB Streptococcus mitis SK321

94.379

100

0.944
  comYB Streptococcus gordonii str. Challis substr. CH1

70.536

99.408

0.701
  comYB Streptococcus mutans UA140

58.621

94.379

0.553
  comYB Streptococcus mutans UA159

58.621

94.379

0.553
  comGB Lactococcus lactis subsp. cremoris KW2

50.299

98.817

0.497

Multiple sequence alignment