Detailed information NTG0337257

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: EQH37_RS10900
• Genome accession: NZ_CP035243
• Coordinates: 519176..519763 (-)
• Length: 195 a.a.
• NCBI ID: WP_054370532.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain TVO_1901946
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 514176..524763

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH37_RS02635 (EQH37_02795)	-	514638..515978 (+)	1341	WP_001099892.1	sensor histidine kinase	-
EQH37_RS02640 (EQH37_02800)	blpC	516022..516177 (-)	156	WP_000358811.1	quorum-sensing system pheromone BlpC	-
EQH37_RS02645 (EQH37_02805)	-	516234..517595 (-)	1362	WP_054407076.1	bacteriocin secretion accessory protein	-
EQH37_RS02650 (EQH37_02810)	comA/nlmT	517606..519282 (-)	1677	WP_306423907.1	peptide cleavage/export ABC transporter	Regulator
EQH37_RS10900	comA/nlmT	519176..519763 (-)	588	WP_054370532.1	cysteine peptidase family C39 domain-containing protein	Regulator
EQH37_RS02655 (EQH37_02815)	-	520053..520256 (+)	204	WP_001093272.1	bacteriocin class II family protein	-
EQH37_RS02660 (EQH37_02820)	-	520574..520777 (+)	204	WP_000411016.1	hypothetical protein	-
EQH37_RS02665 (EQH37_02830)	-	521780..522584 (+)	805	Protein_537	IS5 family transposase	-
EQH37_RS02670 (EQH37_02835)	blpM	522737..522991 (+)	255	WP_000379877.1	two-peptide bacteriocin subunit BlpM	-
EQH37_RS02675 (EQH37_02840)	blpN	523007..523210 (+)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
EQH37_RS02680 (EQH37_02850)	-	523454..523687 (+)	234	WP_054407078.1	hypothetical protein	-
EQH37_RS02685 (EQH37_02855)	-	523719..524408 (+)	690	WP_000760527.1	CPBP family intramembrane glutamic endopeptidase	-
EQH37_RS02690 (EQH37_02860)	blpZ	524450..524683 (+)	234	WP_000276498.1	immunity protein BlpZ	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22326.77 Da
• Isoelectric Point: 9.6188

>NTDB_id=337257 EQH37_RS10900 WP_054370532.1 519176..519763(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901946]
MTSYKRTFVPQIDARDCSVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLAPKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLISHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=337257 EQH37_RS10900 WP_054370532.1 519176..519763(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901946]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTAGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTCCCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTAGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	67.763	77.949	0.528
comA	Streptococcus mitis NCTC 12261	61.935	79.487	0.492
comA	Streptococcus mitis SK321	61.29	79.487	0.487
comA	Streptococcus pneumoniae TIGR4	60.645	79.487	0.482
comA	Streptococcus pneumoniae Rx1	60.645	79.487	0.482
comA	Streptococcus pneumoniae D39	60.645	79.487	0.482
comA	Streptococcus pneumoniae R6	60.645	79.487	0.482
comA	Streptococcus gordonii str. Challis substr. CH1	58.71	79.487	0.467