Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   EQH37_RS02650 Genome accession   NZ_CP035243
Coordinates   517606..519282 (-) Length   558 a.a.
NCBI ID   WP_306423907.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain TVO_1901946     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 512606..524282
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EQH37_RS02620 (EQH37_02780) - 512938..513267 (-) 330 WP_047499345.1 hypothetical protein -
  EQH37_RS02625 (EQH37_02785) - 513544..513882 (+) 339 WP_000682137.1 LytTR family DNA-binding domain-containing protein -
  EQH37_RS02630 (EQH37_02790) comE/blpR 513887..514624 (+) 738 WP_001219137.1 LytTR family DNA-binding domain-containing protein Regulator
  EQH37_RS02635 (EQH37_02795) - 514638..515978 (+) 1341 WP_001099892.1 sensor histidine kinase -
  EQH37_RS02640 (EQH37_02800) blpC 516022..516177 (-) 156 WP_000358811.1 quorum-sensing system pheromone BlpC -
  EQH37_RS02645 (EQH37_02805) - 516234..517595 (-) 1362 WP_054407076.1 bacteriocin secretion accessory protein -
  EQH37_RS02650 (EQH37_02810) comA/nlmT 517606..519282 (-) 1677 WP_306423907.1 peptide cleavage/export ABC transporter Regulator
  EQH37_RS10900 comA/nlmT 519176..519763 (-) 588 WP_054370532.1 cysteine peptidase family C39 domain-containing protein Regulator
  EQH37_RS02655 (EQH37_02815) - 520053..520256 (+) 204 WP_001093272.1 bacteriocin class II family protein -
  EQH37_RS02660 (EQH37_02820) - 520574..520777 (+) 204 WP_000411016.1 hypothetical protein -
  EQH37_RS02665 (EQH37_02830) - 521780..522584 (+) 805 Protein_537 IS5 family transposase -
  EQH37_RS02670 (EQH37_02835) blpM 522737..522991 (+) 255 WP_000379877.1 two-peptide bacteriocin subunit BlpM -
  EQH37_RS02675 (EQH37_02840) blpN 523007..523210 (+) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  EQH37_RS02680 (EQH37_02850) - 523454..523687 (+) 234 WP_054407078.1 hypothetical protein -

Sequence

Protein


Download         Length: 558 a.a.        Molecular weight: 62949.24 Da        Isoelectric Point: 6.7844

>NTDB_id=337193 EQH37_RS02650 WP_306423907.1 517606..519282(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901946]
MIFKQKSLIAYIVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSI
DVILSYIRHIFELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLLSIPIYM
FIIFSFMKPFEKMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTK
LVLNILILWFGAQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHF
LMGDIEFDDLSYKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRH
INYLPQQAYIFNGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKA
PVLILDEATSGLDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1677 bp        

>NTDB_id=337193 EQH37_RS02650 WP_306423907.1 517606..519282(-) (comA/nlmT) [Streptococcus pneumoniae strain TVO_1901946]
CTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTAGTCACTATTATCAATATAGGTGGTTC
TTACTATCTCCAAGGAATCTTGGATGAATACATTCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGG
TTATCACCTATATCCTCCAACAAGTCATGAGCTTCTCCAGAGATTATCTCCTAACCGTTCTGAGCCAGAGATTAAGCATT
GATGTGATTTTATCCTATATTCGCCATATTTTTGAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCAT
TTCACGGTTCACAGATGCTAACTCTATTATAGATGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTC
TGATTCTTGTAGGGGGCGTCTTACTGGCACAAAACCCTAATCTCTTCCTCCTTTCTCTTCTTTCCATTCCTATATACATG
TTCATCATCTTTTCTTTTATGAAACCTTTTGAAAAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGC
CATTATCGAAGATATCAACGGGATTGAAACTATAAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCG
AATTTGTAGATTATTTGGAAAAATCCTTTAAGCTCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAA
TTAGTTCTGAATATCCTTATCCTATGGTTTGGCGCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTAC
CTTTAACACACTTTTTTCTTACTTTACAACTCCTATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGG
TCGCTAATAACCGTTTGAACGAAGTCTATCTAGTCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTT
TTGATGGGCGATATTGAATTTGATGACCTTTCTTATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCAC
GATTAAACAAGGAGATAAGGTTAGCCTAGTTGGAGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATT
TCTTTGAACCCTACAAAGGGCATATTTCCATCAATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCAT
ATTAATTACCTACCCCAACAAGCCTATATCTTTAATGGCTCTATCTTGGAAAATTTAACCTTGGGCGGTAATCATATGAT
TAGCCAAGAAGATATTCTAAGAGCTTGTGAATTAGCTGAAATCCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAA
CTCAGCTCTCTGATGGAGCTGGTCTATCAGGAGGACAGAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCT
CCTGTTTTAATACTAGACGAAGCTACTAGCGGTCTTGATGTCTTGACTGAGAAAAAAGTTATAGATAATCTTATGTCCCT
AACTGATAAAACCATTCTCTTTGTAGCCCATCGTCTCAGTATAGCCGAACGAACTAACCGTGTCATTGTTCTTGACCAGG
GGAAAATCATTGAAGTTGGTAGTCACCAAGAGTTAATGCAGGCGCAAGGCTTCTACCATCATCTGTTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(341-490)

ABC transporter transmembrane region (ABC_membrane)

(10-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.25

99.821

0.731
  comA Streptococcus mitis NCTC 12261

67.742

100

0.677
  comA Streptococcus pneumoniae D39

67.384

100

0.674
  comA Streptococcus pneumoniae R6

67.384

100

0.674
  comA Streptococcus pneumoniae Rx1

67.384

100

0.674
  comA Streptococcus gordonii str. Challis substr. CH1

67.084

100

0.672
  comA Streptococcus mitis SK321

67.204

100

0.672
  comA Streptococcus pneumoniae TIGR4

67.025

100

0.67

Multiple sequence alignment