Detailed information NTG0337233

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: EQH37_RS09440
• Genome accession: NZ_CP035243
• Coordinates: 1879747..1880757 (-)
• Length: 336 a.a.
• NCBI ID: WP_000990607.1
• Uniprot ID: A0A0B7LZL8
• Organism: Streptococcus pneumoniae strain TVO_1901946
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1874747..1885757

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EQH37_RS09415 (EQH37_09955)	-	1874825..1876039 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
EQH37_RS09420 (EQH37_09960)	-	1876195..1876477 (-)	283	Protein_1868	hypothetical protein	-
EQH37_RS09425 (EQH37_09965)	-	1876548..1877000 (+)	453	WP_000079148.1	universal stress protein	-
EQH37_RS09430 (EQH37_09970)	-	1877035..1878423 (-)	1389	WP_000453139.1	Cof-type HAD-IIB family hydrolase	-
EQH37_RS09435 (EQH37_09975)	-	1878489..1879451 (+)	963	WP_001124771.1	asparaginase	-
EQH37_RS09440 (EQH37_09980)	ccpA	1879747..1880757 (-)	1011	WP_000990607.1	catabolite control protein A	Regulator
EQH37_RS09445 (EQH37_09985)	-	1881182..1881781 (-)	600	WP_000866724.1	response regulator transcription factor	-
EQH37_RS09450 (EQH37_09990)	-	1881783..1882880 (-)	1098	WP_050148143.1	sensor histidine kinase	-
EQH37_RS09455 (EQH37_09995)	-	1882880..1883617 (-)	738	WP_000832843.1	ABC transporter permease	-
EQH37_RS09460 (EQH37_10000)	-	1883619..1884503 (-)	885	WP_000219356.1	ABC transporter ATP-binding protein	-
EQH37_RS09465 (EQH37_10005)	-	1884490..1884684 (-)	195	WP_000820182.1	hypothetical protein	-
EQH37_RS09470 (EQH37_10010)	-	1884681..1884887 (-)	207	WP_000503437.1	hypothetical protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37073.01 Da
• Isoelectric Point: 5.3212

>NTDB_id=337233 EQH37_RS09440 WP_000990607.1 1879747..1880757(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901946]
MNADDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
SLAKGIDDIAEMYKYNIVLANSDEDNEKEVSVVNTLFSKQVDGIIYMGYHLTDKIRSEFSRSRTPIVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLAKENERIAFVSGPLVDDINGKVRLVGYKETLKKAGITYSEGLVFESKYSYDDGYALAERLISSN
ATAAVVTGDELAAGVLNGLADKGVSVPEDFEIITSDDSQISRFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERSSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=337233 EQH37_RS09440 WP_000990607.1 1879747..1880757(-) (ccpA) [Streptococcus pneumoniae strain TVO_1901946]
ATGAATGCAGATGATACAGTAACCATTTATGATGTCGCTCGTGAAGCAGGTGTTTCCATGGCGACGGTCAGCCGTGTGGT
CAATGGCAATAAAAATGTAAAAGAGAATACCCGTAAAAAAGTGCTAGAGGTAATTGATCGTTTGGATTATCGTCCAAATG
CAGTTGCGCGTGGTCTTGCAAGTAAAAAGACAACCACTGTCGGTGTCGTGATTCCAAATATTACCAATGGTTATTTTTCG
AGTTTGGCTAAGGGGATTGATGATATTGCAGAAATGTACAAGTACAATATTGTCCTAGCTAATAGCGATGAAGATAACGA
GAAAGAAGTTTCTGTTGTCAATACCCTCTTTTCAAAGCAGGTAGATGGCATTATCTATATGGGTTATCACTTGACAGATA
AAATTCGCTCAGAATTTTCGCGTTCACGTACTCCGATTGTTCTCGCAGGAACTGTCGATGTTGAGCACCAGTTGCCCAGT
GTCAATATTGACTATAAGCAAGCAACAATTGATGCAGTGAGTTACCTTGCTAAAGAAAATGAGCGTATTGCTTTCGTTAG
CGGTCCGCTAGTGGATGACATCAATGGTAAGGTTCGTTTAGTTGGCTACAAGGAAACCTTGAAAAAAGCAGGAATCACTT
ATAGTGAGGGTTTGGTATTTGAATCTAAATATAGCTATGATGATGGTTACGCCTTAGCAGAGCGTTTGATTTCATCAAAT
GCAACTGCAGCAGTTGTGACAGGTGATGAGTTGGCAGCAGGAGTCTTGAACGGTTTGGCTGATAAGGGTGTTTCTGTGCC
AGAAGATTTTGAAATTATTACTAGTGATGATTCACAAATCTCACGCTTTACCCGTCCAAACTTGACAACGATTGCCCAAC
CTCTTTATGACCTTGGTGCCATTAGTATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAACGTAGCTCAACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A0B7LZL8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	99.702	100	0.997
ccpA	Streptococcus gordonii str. Challis substr. CH1	87.126	99.405	0.866
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568