Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   FY406_RS00680 Genome accession   NZ_CP043405
Coordinates   151170..151832 (-) Length   220 a.a.
NCBI ID   WP_003089221.1    Uniprot ID   A0ABN0GV04
Organism   Streptococcus ratti strain ATCC 31377     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 146170..156832
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY406_RS00665 (FY406_00665) holA 146715..147752 (-) 1038 WP_003090709.1 DNA polymerase III subunit delta -
  FY406_RS00670 (FY406_00670) - 148086..148697 (-) 612 WP_003089215.1 DUF805 domain-containing protein -
  FY406_RS00675 (FY406_00675) comEC/celB 148946..151168 (-) 2223 WP_003089219.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  FY406_RS00680 (FY406_00680) comEA/celA/cilE 151170..151832 (-) 663 WP_003089221.1 helix-hairpin-helix domain-containing protein Machinery gene
  FY406_RS00685 (FY406_00685) - 151999..152751 (-) 753 WP_003089224.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  FY406_RS00690 (FY406_00690) - 153408..153688 (+) 281 Protein_134 HXXEE domain-containing protein -
  FY406_RS00695 (FY406_00695) - 153735..154742 (+) 1008 WP_003089235.1 GIY-YIG nuclease family protein -
  FY406_RS00700 (FY406_00700) - 155158..155355 (-) 198 WP_003089239.1 hypothetical protein -
  FY406_RS00705 (FY406_00705) - 155500..155859 (-) 360 WP_003089240.1 hypothetical protein -
  FY406_RS00710 (FY406_00710) - 155903..156151 (-) 249 WP_003089243.1 hypothetical protein -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23951.86 Da        Isoelectric Point: 4.8484

>NTDB_id=336796 FY406_RS00680 WP_003089221.1 151170..151832(-) (comEA/celA/cilE) [Streptococcus ratti strain ATCC 31377]
MIEEILDKFRENKRLLTAVVVFAVLGLGLYFLSSNGKEDKNHLDRSQEQYLSSATLSAHSEQTKQTQAASTIMVDVKGAV
KKQGVYSLPADSRVNELIEKAGGFSEKADRKSVNLAQKLQDEAVIYVASIGEDISVVDNSQKAAVNQSSNSQPAVQDKIN
LNTASLADLQTISGIGEKRAQDIIDYREANGGFQSIDDLKNISGIGEKTFEKLKDLVSID

Nucleotide


Download         Length: 663 bp        

>NTDB_id=336796 FY406_RS00680 WP_003089221.1 151170..151832(-) (comEA/celA/cilE) [Streptococcus ratti strain ATCC 31377]
ATGATAGAAGAAATTTTGGATAAATTTAGAGAAAATAAGCGGCTCCTTACTGCAGTCGTTGTTTTTGCTGTCTTGGGACT
GGGTCTTTATTTTTTGTCTTCCAATGGAAAAGAGGATAAGAATCATTTGGACCGCTCACAAGAACAGTATCTTTCATCAG
CAACTTTATCTGCTCATTCGGAACAAACAAAGCAAACCCAGGCTGCTTCAACAATAATGGTTGATGTCAAAGGCGCAGTG
AAAAAACAAGGCGTGTACAGTCTGCCGGCTGACAGCCGTGTTAACGAGCTTATTGAGAAGGCTGGCGGTTTTTCTGAAAA
AGCAGACCGCAAGTCAGTCAATCTTGCGCAAAAGCTGCAGGATGAGGCTGTTATTTACGTCGCATCCATCGGAGAAGACA
TCAGTGTTGTTGATAATTCTCAAAAAGCAGCGGTTAATCAAAGCAGCAATTCTCAGCCAGCAGTACAGGATAAGATCAAT
CTAAATACGGCCAGCCTTGCTGATCTCCAAACAATATCGGGCATCGGTGAAAAAAGGGCACAGGATATTATTGATTATCG
TGAAGCTAACGGCGGCTTTCAGTCAATAGATGACTTAAAAAATATTTCCGGCATTGGCGAAAAAACATTTGAAAAGCTGA
AAGACTTGGTGAGTATTGATTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(73-127)

Helix-hairpin-helix motif (HHH_3)

(157-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis SK321

43.363

100

0.445
  comEA Lactococcus lactis subsp. cremoris KW2

42.152

100

0.427
  comEA/celA/cilE Streptococcus mitis NCTC 12261

55.705

67.727

0.377
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

55.705

67.727

0.377
  comEA/celA/cilE Streptococcus pneumoniae R6

55.034

67.727

0.373
  comEA/celA/cilE Streptococcus pneumoniae Rx1

55.034

67.727

0.373
  comEA/celA/cilE Streptococcus pneumoniae D39

55.034

67.727

0.373
  comEA Streptococcus thermophilus LMD-9

55.479

66.364

0.368
  comEA Latilactobacillus sakei subsp. sakei 23K

32.922

100

0.364

Multiple sequence alignment