Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   SPT_RS10120 Genome accession   NC_012469
Coordinates   1904109..1904411 (-) Length   100 a.a.
NCBI ID   WP_000413380.1    Uniprot ID   -
Organism   Streptococcus pneumoniae Taiwan19F-14     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1899109..1909411
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPT_RS10090 (SPT_2037) rnpA 1899795..1900166 (-) 372 WP_000739246.1 ribonuclease P protein component -
  SPT_RS13270 (SPT_2038) - 1900183..1900314 (-) 132 WP_000768904.1 hypothetical protein -
  SPT_RS10095 (SPT_2039) - 1900315..1901505 (-) 1191 WP_000167766.1 acetate kinase -
  SPT_RS10100 (SPT_2040) comYH 1901556..1902509 (-) 954 WP_000345119.1 class I SAM-dependent methyltransferase Machinery gene
  SPT_RS10105 (SPT_2041) - 1902570..1903157 (-) 588 WP_000679774.1 class I SAM-dependent methyltransferase -
  SPT_RS10110 (SPT_2042) comGG/cglG 1903294..1903707 (-) 414 WP_000265630.1 competence type IV pilus minor pilin ComGG Machinery gene
  SPT_RS10115 (SPT_2043) comGF/cglF 1903685..1904146 (-) 462 WP_000250545.1 competence type IV pilus minor pilin ComGF Machinery gene
  SPT_RS10120 (SPT_2044) comGE/cglE 1904109..1904411 (-) 303 WP_000413380.1 competence type IV pilus minor pilin ComGE Machinery gene
  SPT_RS10125 (SPT_2045) comGD/cglD 1904374..1904778 (-) 405 WP_000588005.1 competence type IV pilus minor pilin ComGD Machinery gene
  SPT_RS10130 (SPT_2046) comGC/cglC 1904771..1905097 (-) 327 WP_000738650.1 comG operon protein ComGC Machinery gene
  SPT_RS10135 (SPT_2047) comGB/cglB 1905099..1906115 (-) 1017 WP_013193332.1 competence type IV pilus assembly protein ComGB Machinery gene
  SPT_RS10140 (SPT_2048) comGA/cglA/cilD 1906063..1907004 (-) 942 WP_000249567.1 competence type IV pilus ATPase ComGA Machinery gene
  SPT_RS10145 (SPT_2049) - 1907080..1907445 (-) 366 WP_000286415.1 DUF1033 family protein -
  SPT_RS10150 (SPT_2050) - 1907596..1908654 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11135.11 Da        Isoelectric Point: 9.7273

>NTDB_id=33417 SPT_RS10120 WP_000413380.1 1904109..1904411(-) (comGE/cglE) [Streptococcus pneumoniae Taiwan19F-14]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVAKMALQTGQNQVNINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=33417 SPT_RS10120 WP_000413380.1 1904109..1904411(-) (comGE/cglE) [Streptococcus pneumoniae Taiwan19F-14]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAAGATGGCCTTGCAGACAGGTCAAAATCAGGTAAACATAAACGGAGTTGAGATTCAGGTGTTTTCT
AGCGAAAAGGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus mitis NCTC 12261

99

100

0.99
  comGE/cglE Streptococcus pneumoniae Rx1

99

100

0.99
  comGE/cglE Streptococcus pneumoniae D39

99

100

0.99
  comGE/cglE Streptococcus pneumoniae R6

99

100

0.99
  comGE/cglE Streptococcus pneumoniae TIGR4

99

100

0.99
  comGE/cglE Streptococcus mitis SK321

98

100

0.98
  comYE Streptococcus mutans UA140

43.333

90

0.39
  comYE Streptococcus mutans UA159

43.333

90

0.39

Multiple sequence alignment